Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 4/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19685928 | 0.90 | ESR1 (0.35) | LMNAKDM4EMEN1KMT2AESR1 | |
| SCHEMBL19685930 | 0.90 | ESR1 (0.38) | LMNAKDM4EMEN1KMT2ADHODH | |
| SCHEMBL19686088 | 0.88 | BRD4 (0.38) | LMNAKDM4ETDO2IDO2IDO1 | |
| SCHEMBL19685877 | 0.85 | MAPK8 (0.37) | LMNAMEN1KMT2ATDO2IDO2 | |
| SCHEMBL19685879 | 0.84 | LMNA (0.36) | LMNAKDM4EMEN1KMT2ADHODH | |
| SCHEMBL19685831 | 0.80 | LMNA (0.34) | LMNAKDM4EMEN1KMT2ADHODH | |
| SCHEMBL19686086 | 0.78 | BRD4 (0.40) | LMNAMEN1KMT2ATDO2IDO2 | |
| SCHEMBL19685968 | 0.77 | ATM (0.36) | LMNAKDM4EMEN1KMT2ATDO2 | |
| SCHEMBL19686085 | 0.77 | BRD4 (0.43) | MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL19685934 | 0.77 | ESR1 (0.34) | LMNAKDM4EDHODHESR1ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170352817-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170352817-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | CYC1, CCNA1, CYCS | LMNA 3026/4885KDM4E 1138/4885MEN1 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.