SCHEMBL19686080

SCHEMBL19686080

Cc1cn(C)c(=O)c2ccc(N3c4ccccc4-c4ccccc4Sc4ccccc4-c4ccccc43)cc12

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 13/20 0.43
BRD9 Q9H8M2 1/20 0.39
BRD7 Q9NPI1 1/20 0.39
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.33
PABPC1 P11940 1/20 0.32
APOBEC3A P31941 1/20 0.32
EIF4H Q15056 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19686146 0.86 ESR1 (0.38) BRD4MEN1KMT2ALMNA
SCHEMBL19686085 0.84 BRD4 (0.43) BRD4BRD9BRD7MEN1KMT2A
SCHEMBL19686084 0.83 BRD4 (0.35) BRD4BRD9BRD7
SCHEMBL19685867 0.83 MEN1 (0.35) BRD4MEN1KMT2ALMNAPABPC1
SCHEMBL19685872 0.81 BRD4 (0.43) BRD4BRD9BRD7MEN1KMT2A
SCHEMBL19685859 0.79 BRD4 (0.43) BRD4BRD9BRD7MEN1KMT2A
SCHEMBL19685860 0.79 BRD4 (0.43) BRD4BRD9BRD7MEN1KMT2A
SCHEMBL19685730 0.79 BRD4 (0.33) BRD4BRD9BRD7
SCHEMBL19685734 0.76 BRD4 (0.41) BRD4BRD9BRD7MEN1KMT2A
SCHEMBL19685946 0.76 ALDH1A1 (0.42) MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS BRD4 740/4885BRD9 1480/4885BRD7 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.