SCHEMBL19686102

SCHEMBL19686102

Cc1coc(=O)c2ccc(N3c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc43)cc12

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ITGB2 P05107 1/20 0.31
ICAM1 P05362 1/20 0.31
ITGAL P20701 1/20 0.31
CNR1 P21554 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
MAPK1 P28482 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685902 0.95 ALDH1A1 (0.32) ITGB2ICAM1ITGALCNR1GPR55
SCHEMBL19686103 0.88 MEN1 (0.35) MEN1KMT2AUSP2ALDH1A1HSD17B10
SCHEMBL19686111 0.86 USP2 (0.32) USP2
SCHEMBL19686112 0.85 HDAC6 (0.30)
SCHEMBL19685901 0.84 MEN1 (0.35) MEN1KMT2AALDH1A1NPSR1
SCHEMBL19686056 0.84 MEN1 (0.35) MEN1KMT2AUSP2ALDH1A1NPSR1
SCHEMBL19685675 0.83 ALDH1A1 (0.35) MEN1KMT2AALDH1A1NPSR1HSD17B10
SCHEMBL19686009 0.83 ALDH1A1 (0.37) MEN1KMT2AUSP2ALDH1A1TP53
SCHEMBL19686058 0.82 USP2 (0.32) USP2ALDH1A1NPSR1
SCHEMBL19685798 0.81 HDAC6 (0.30) ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS ITGB2 2425/4885ICAM1 1546/4885ITGAL 2258/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS ITGB2 2425/4885ICAM1 1546/4885ITGAL 2258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.