SCHEMBL19686103

SCHEMBL19686103

Cc1coc(=O)c2ccc(N3c4ccccc4C4(c5ccccc5-c5ccccc54)c4ccccc43)cc12

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PGR P06401 9/20 0.34
KCNA3 P22001 5/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
KDM4E B2RXH2 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30
GRM1 Q13255 1/20 0.30
GRM4 Q14833 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19686056 0.95 MEN1 (0.35) MEN1KMT2APGRKCNA3ESR1
SCHEMBL19686106 0.91 PGR (0.36) MEN1KMT2APGRALDH1A1
SCHEMBL19686111 0.89 USP2 (0.32) USP2
SCHEMBL19686102 0.88 ITGB2 (0.31) MEN1KMT2AUSP2ALDH1A1HSD17B10
SCHEMBL19686112 0.88 HDAC6 (0.30)
SCHEMBL19686061 0.87 PGR (0.36) MEN1KMT2APGR
SCHEMBL19686058 0.84 USP2 (0.32) USP2ALDH1A1
SCHEMBL19685902 0.84 ALDH1A1 (0.32) MEN1KMT2AUSP2ALDH1A1HPGD
SCHEMBL19685798 0.83 HDAC6 (0.30) ALDH1A1
SCHEMBL19686011 0.83 ALDH1A1 (0.42) MEN1KMT2APGRKCNA3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS MEN1 644/4885KMT2A 1444/4885PGR 607/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS MEN1 644/4885KMT2A 1444/4885PGR 607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.