Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 3/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687001 | 0.83 | IDH1 (0.39) | PDE4DROCK2IDH1IDH2NOS3 | |
| SCHEMBL31127199 | 0.83 | IDH1 (0.39) | PDE4DROCK2IDH1IDH2NOS3 | |
| SCHEMBL19686287 | 0.83 | IDH1 (0.39) | PDE4DROCK2IDH1IDH2NOS3 | |
| SCHEMBL31127431 | 0.83 | ADORA3 (0.34) | PDE4DROCK2IDH1IDH2NOS3 | |
| SCHEMBL21144356 | 0.83 | ADORA3 (0.34) | PDE4DROCK2IDH1IDH2NOS3 | |
| SCHEMBL19687003 | 0.83 | IDH1 (0.38) | PDE4DROCK2IDH1IDH2NOS3 | |
| SCHEMBL19687005 | 0.83 | IDH1 (0.38) | PDE4DROCK2IDH1IDH2NOS1 | |
| SCHEMBL21144088 | 0.82 | GPR119 (0.36) | PDE4DSMN1; SMN2ROCK2IDH1IDH2 | |
| SCHEMBL31127073 | 0.82 | GPR119 (0.36) | PDE4DSMN1; SMN2ROCK2IDH1IDH2 | |
| SCHEMBL19687244 | 0.82 | IDH1 (0.38) | PDE4DROCK2IDH1IDH2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774064-B2 | Potassium channel modulators | CADENT THERAPEUTICS, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | NOVARTIS AG (CH) | 2019-07-18 | — | — | US | disclosed |
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774064-B2 | Potassium channel modulators | KCNJ11, KCNJ2, KCNJ1 | WHR1 4419/4885EHMT2 3277/4885EHMT1 2638/4885 |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | KCNJ11, KCNJ2, KCNJ1 | WHR1 4419/4885EHMT2 3277/4885EHMT1 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.