Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.42 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.42 |
| ▸ | PPP5C | P53041 | 1/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533614 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL27496 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL3130301 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL13216620 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL196877 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL12268145 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL13197282 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL16704819 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL13397502 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL12549702 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336781-B2 | Recyclable metathesis catalysts | THE TRUSTEES OF BOSTON COLLEGE (US) | 2019-07-02 | — | — | US | disclosed |
| EP-3475267-A1 | PRODUCTION OF SULFONYL AZIDE ANHYDRIDE | Dow Global Technologies, LLC (US) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017223164-A1 | PRODUCTION OF SULFONYL AZIDE ANHYDRIDE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-12-28 | — | — | WO | disclosed |
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-09-07 | — | — | US | disclosed |
| US-9676676-B2 | Selective olefin metathesis with cyclometalated ruthenium complexes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-06-13 | — | — | US | disclosed |
| US-9676676-B2 | Selective olefin metathesis with cyclometalated ruthenium complexes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160185684-A1 | SELECTIVE OLEFIN METATHESIS WITH CYCLOMETALATED RUTHENIUM COMPLEXES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
| WO-2016020526-A1 | INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | JANSSEN SCIENCES IRELAND UC (IE) | 2016-02-11 | — | — | WO | disclosed |
| EP-2785763-A1 | FUNCTIONALIZATION OF VINYL TERMINATED POLYMERS BY RING OPENING CROSS METATHESIS | ExxonMobil Chemical Patents Inc. (US) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013081726-A1 | FUNCTIONALIZATION OF VINYL TERMINATED POLYMERS BY RING OPENING CROSS METATHESIS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-06-06 | — | — | WO | disclosed |
| US-8110679-B2 | Nanofilm and membrane compositions | COVALENT PARTNERS LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-20090114596-A1 | NANOFILM AND MEMBRANE COMPOSITIONS | COVALENT PARTNERS LLC | 2009-05-07 | — | — | US | disclosed |
| WO-1993000395-A1 | ADDITIVES WHICH STABILIZE HYDROHALOCARBON BLOWING AGENT IN POLYURETHANE AND POLYISOCYANURATE FOAM FORMULATIONS DURING POLYMERIZATION | ALLIED-SIGNAL INC. (US) | 1993-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | HAVCR2, HCCS, LIPC | ALDH1A1 1148/4885TDP1 4689/4885SMN1; SMN2 4871/4885 |
| US-10336781-B2 | Recyclable metathesis catalysts | DNMT1, CARM1, ZMYND8 | ALDH1A1 2343/4885TDP1 2176/4885SMN1; SMN2 2000/4885 |
| US-20160185684-A1 | SELECTIVE OLEFIN METATHESIS WITH CYCLOMETALATED RUTHENIUM COMPLEXES | ZDHHC7, COASY, ZDHHC2 | ALDH1A1 3001/4885TDP1 4076/4885SMN1; SMN2 4506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.