Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.44 |
| ▸ | USP2 | O75604 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687703 | 0.95 | CYP3A4 (0.43) | RORCCYP3A4CYP2D6USP2TSHR | |
| SCHEMBL19838241 | 0.81 | CYP3A4 (0.66) | CYP3A4CYP2D6USP2TSHRCYP1A2 | |
| SCHEMBL20556708 | 0.77 | ERN1 (0.56) | RORCCYP3A4CYP2D6TSHRCYP1A2 | |
| SCHEMBL982298 | 0.77 | PDE4A (0.39) | CYP3A4CYP2D6USP2TSHRCYP1A2 | |
| SCHEMBL19687609 | 0.77 | RORC (0.51) | RORCCYP3A4CYP2D6USP2TSHR | |
| SCHEMBL21276348 | 0.77 | MGLL (0.53) | RORCCYP3A4CYP2D6USP2TSHR | |
| SCHEMBL16090764 | 0.77 | NR1H2 (0.48) | — | |
| SCHEMBL30620506 | 0.76 | GPR183 (0.52) | RORCCYP3A4CYP2D6USP2TSHR | |
| SCHEMBL19687697 | 0.76 | RORC (0.52) | RORCCYP3A4CYP2D6USP2TSHR | |
| SCHEMBL1426231 | 0.76 | CYP2D6 (0.64) | CYP3A4CYP2D6USP2TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |