Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | GPR183 | P32249 | 5/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | VEGFA | P15692 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30620506 | 0.90 | GPR183 (0.52) | MGLLGPR183RORCCYP2D6CYP3A4 | |
| SCHEMBL1426231 | 0.89 | CYP2D6 (0.64) | CYP2D6CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20556708 | 0.89 | ERN1 (0.56) | MGLLGPR183RORCCYP2D6CYP3A4 | |
| SCHEMBL31565342 | 0.87 | CYP3A4 (0.60) | CYP2D6CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19838241 | 0.87 | CYP3A4 (0.66) | CYP2D6CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL896978 | 0.85 | CYP2D6 (0.50) | MGLLRORCCYP2D6CYP3A4TSHR | |
| SCHEMBL8060453 | 0.84 | CYP2D6 (0.72) | CYP2D6CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29468752 | 0.84 | RORC (0.53) | MGLLGPR183RORCCYP2D6CYP3A4 | |
| SCHEMBL30620521 | 0.84 | RORC (0.49) | MGLLGPR183RORCCYP2D6CYP3A4 | |
| SCHEMBL21262272 | 0.83 | CYP2D6 (0.60) | CYP2D6CYP3A4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385057-B2 | Pyrazole compounds and methods of making and using same | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2019-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385057-B2 | Pyrazole compounds and methods of making and using same | FAAH, FAAH2, MGLL | MGLL 3/4885GPR183 709/4885RORC 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.