Sugi Predict

Sugi Predict / Compounds / SCHEMBL19687837

SCHEMBL19687837

SCHEMBL19687837

CCCCCCCC(C)(CCCCCC)N1C(=O)C=CC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 7/20 0.50
▸ FAAH O00519 4/20 0.50
▸ PTGS1 P23219 3/20 0.50
▸ PTGS2 P35354 3/20 0.50
▸ ALDH1A1 P00352 2/20 0.35
▸ LMNA P02545 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ NPSR1 Q6W5P4 2/20 0.35
▸ GMNN O75496 1/20 0.35
▸ THPO P40225 1/20 0.35
▸ BLM P54132 1/20 0.35
▸ PMP22 Q01453 1/20 0.35
▸ HSP90AA1 P07900 1/20 0.34
▸ TLR9 Q9NR96 1/20 0.34
▸ TP53 P04637 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ XBP1 P17861 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18774136 1.00 MGLL (0.50) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL19687894 1.00 MGLL (0.50) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL20431750 1.00 MGLL (0.50) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL23619533 0.93 MGLL (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL22778931 0.93 MGLL (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL18914558 0.85 MGLL (0.50) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL18569569 0.85 MGLL (0.50) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL21123633 0.84 MGLL (0.41) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL18576988 0.82 MGLL (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL22604621 0.79 MGLL (0.48) MGLLFAAHPTGS1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370922-B2 Ultra bright polymeric dyes with peptide backbones SONY CORPORATION (JP) 2022-06-28 — — US disclosed
US-10989715-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION (JP) 2021-04-27 — — US disclosed
US-20210106690-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2021-04-15 — — US disclosed
US-20210096135-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2021-04-01 — — US disclosed
US-20200353094-A1 PHOSPHOALKYL RIBOSE POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS Sony Group Corporation (JP) 2020-11-12 — — US disclosed
US-20200284798-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2020-09-10 — — US disclosed
US-10603386-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2020-03-31 — — US disclosed
US-20190194386-A1 Conducting Polymers and Uses Thereof AUCKLAND UNISERVICES LIMITED (NZ) 2019-06-27 — — US disclosed
US-20190153232-A1 ULTRA BRIGHT POLYMERIC DYES WITH PEPTIDE BACKBONES SONY CORPORATION (JP) 2019-05-23 — — US disclosed
US-10273224-B2 Substituted pyrimidine compounds, compositions and medicinal applications thereof JUBILANT BIOSYS LIMITED (IN) 2019-04-30 — — US disclosed
US-9901567-B2 Substituted CC-1065 analogs and their conjugates SYNTARGA B.V. (NL) 2018-02-27 — — US disclosed
US-9872918-B2 Hydroxyl-polymer-drug-protein conjugates MERSANA THERAPEUTICS, INC. (US) 2018-01-23 — — US disclosed
US-20170348424-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2017-12-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190153232-A1 ULTRA BRIGHT POLYMERIC DYES WITH PEPTIDE BACKBONES IK, NGLY1, MRPL21 MGLL 1625/4885FAAH 4638/4885PTGS1 3073/4885
US-20200284798-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 MGLL 3916/4885FAAH 4738/4885PTGS1 3383/4885
US-20170348424-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, CLTB, BRAP MGLL 1847/4885FAAH 3922/4885PTGS1 2677/4885
US-20200353094-A1 PHOSPHOALKYL RIBOSE POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS PARP1, PARP11, PHOSPHO1 MGLL 1663/4885FAAH 4784/4885PTGS1 3406/4885
US-10989715-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups IK, MTCL3, RRM1 MGLL 3916/4885FAAH 4738/4885PTGS1 3383/4885
US-20210096135-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 MGLL 3916/4885FAAH 4738/4885PTGS1 3383/4885
US-20190194386-A1 Conducting Polymers and Uses Thereof POLI, PARG, PARN MGLL 3807/4885FAAH 4456/4885PTGS1 3060/4885
US-20210106690-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, CLTB, BRAP MGLL 1643/4885FAAH 3652/4885PTGS1 2894/4885
US-10603386-B2 Protein-polymer-drug conjugates PBRM1, CLTB, BRAP MGLL 1714/4885FAAH 3726/4885PTGS1 2904/4885
US-11370922-B2 Ultra bright polymeric dyes with peptide backbones IK, NGLY1, MRPL21 MGLL 1625/4885FAAH 4638/4885PTGS1 3073/4885
US-10273224-B2 Substituted pyrimidine compounds, compositions and medicinal applications thereof TYMP, EGFR, TK1 MGLL 4408/4885FAAH 4623/4885PTGS1 2270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.