Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 8/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27573365 | 0.98 | ADRB1 (0.42) | ADRB1SYKTAS2R14LOXL2LOX | |
| SCHEMBL1660907 | 0.77 | SYK (0.38) | SYK | |
| SCHEMBL11015703 | 0.77 | CYP3A4 (0.40) | — | |
| SCHEMBL27285543 | 0.74 | ADRB1 (0.44) | ADRB1SYKTAS2R14LOXL2LOX | |
| SCHEMBL3295825 | 0.74 | MALT1 (0.47) | ADRB1SYKTAS2R14LOXL2LOX | |
| SCHEMBL171691 | 0.73 | ADRB1 (0.43) | ADRB1SYKTAS2R14LOXL2LOX | |
| SCHEMBL345262 | 0.73 | HSP90AA1 (0.45) | ADRB1SYKLOXL2LOX | |
| SCHEMBL4428210 | 0.73 | ADRB1 (0.43) | ADRB1SYKTAS2R14LOXL2LOX | |
| SCHEMBL2873952 | 0.73 | ADRB1 (0.43) | ADRB1SYKTAS2R14LOXL2LOX | |
| SCHEMBL482717 | 0.73 | TRPV4 (0.45) | ADRB1SYKTAS2R14LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626691-B | The preparation method of ZEN 90160 | Shanghai Heben-Eastsun Medicaments Co., Ltd. (CN) | 2015-10-21 | — | — | CN | claimed |
| CN-102911123-B | Preparation method of 2-chloro trifluoromethyl pyrimidine compound | SHANGHAI TITAN TECHNOLOGY CO LTD | 2015-04-22 | — | — | CN | claimed |
| CN-103626691-A | Picoxystrobin preparation method | SHANGHAI HEBEN EASTSUN MEDICAMENTS CO LTD | 2014-03-12 | — | — | CN | claimed |
| CN-101525315-B | Chemical process for extraction of 2-hydroxy pyridine derivatives, 2-hydroxyquinoline, and 2-hydroxybenzothiazole | DU PONT | 2013-12-25 | — | — | CN | claimed |
| CN-102911123-A | Preparation method of 2-chloro trifluoromethyl pyrimidine compound | SHANGHAI TITAN TECHNOLOGY CO LTD | 2013-02-06 | — | — | CN | claimed |
| CN-101525315-A | Chemical process for the extraction of 2-hydroxy pyridine derivatives, 2-hydroxyquinoline, and 2-hydroxybenzothiazole | SYNGENTA LTD (GB) | 2009-09-09 | — | — | CN | claimed |
| CN-100494176-C | Method for extracting alkali metal or calcium salt of halogen or halogenated alkyl substituted 2-hydroxypyridine, 2-hydroxyquinoline and 2-hydroxybenzothiazole | SYNGENTA LTD (GB) | 2009-06-03 | — | — | CN | claimed |
| CN-1443169-A | Chemical method for extracting 2-hydroxypyridine derivatives, 2-hydroxyquinoline and 2-hydroxybenzothiazole | SYNGENTA LTD (GB) | 2003-09-17 | — | — | CN | claimed |
| US-6271400-B2 | SILICON BASED ANHYDROUS OXIDANT; LIGAND; CATALYTIC ORGANO OR INORGANO RHENIUM OXIDE; CONTROLLING EXCESS WATER CONCENTRATION AND MAXIMIZING MONOPEROXOCOMPLEX FORMATION. | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-07 | — | — | US | claimed |
| US-20010001798-A1 | EPOXIDATION OF OLEFINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-05-24 | — | — | US | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| US-20210277221-A1 | RESIN COMPOSITION, LAMINATE, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE FOR MOUNTING SEMICONDUCTOR WITH RESIN COMPOSITION LAYER AND SEMICONDUCTOR DEVICE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-09-09 | — | — | US | disclosed |
| EP-0533870-A1 | NEMATOCIDE PYRIMIDINE DERIVATIVES | ZENECA LIMITED (GB) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992017457-A1 | NEMATOCIDE PYRIMIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506270-A1 | Nematocide pyrimidine derivatives | ZENECA LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| EP-0163280-A1 | Pyrimidylphosphoric acid esters, process for their preparation and their use for pest control | BASF Aktiengesellschaft (DE) | 1985-12-04 | — | — | EP | disclosed |