Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30230348 | 1.00 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1ADRB1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL31336789 | 0.98 | LOXL2 (0.44) | HSP90AA1HSP90AB1ADRB1KDM4EHSD17B10 | |
| SCHEMBL29310180 | 0.78 | NUDT1 (0.44) | HSP90AA1LOXL2HRH4AURKAPRKACA | |
| SCHEMBL179501 | 0.77 | NUDT1 (0.48) | HSP90AA1HSD17B10SYKHRH4AURKA | |
| SCHEMBL17420494 | 0.77 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1HSD17B10HRH4AURKA | |
| SCHEMBL3295825 | 0.74 | MALT1 (0.47) | ADRB1LOXL2SYKLOX | |
| SCHEMBL27285543 | 0.74 | ADRB1 (0.44) | ADRB1LOXL2SYKLOX | |
| SCHEMBL31728177 | 0.74 | NUDT1 (0.46) | HSP90AA1HRH4AURKAPRKACAADORA2A | |
| SCHEMBL2036623 | 0.74 | SYK (0.43) | SYK | |
| SCHEMBL1968808 | 0.73 | ADRB1 (0.43) | ADRB1LOXL2SYKLOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | claimed |
| CN-120040371-A | Compound capable of degrading MYC in targeted manner and application thereof | 中国医学科学院医药生物技术研究所 | 2025-05-27 | — | — | CN | claimed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| WO-2024063670-A1 | CYCLIN-DEPENDENT KINASE 7 INHIBITORS | Акционерное общество "БИОКАД" | 2024-03-28 | — | — | WO | claimed |
| CN-117165078-A | Cyanate resin with low dielectric loss suitable for winding forming process, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2023-12-05 | — | — | CN | claimed |
| WO-2023172957-A1 | THAIZOLE-PYRIMDIINE CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2023-09-14 | — | — | WO | claimed |
| CN-115050893-A | Perovskite solar cell based on alkaloid additive | 安徽大学 | 2022-09-13 | — | — | CN | claimed |
| EP-3559000-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION METHODS AND USES THEIROF | Betta Pharmaceuticals Co., Ltd. (CN) | 2019-10-30 | — | — | EP | claimed |
| EP-3458035-A1 | TREATMENT OF SKIN LESIONS | PIQUR Therapeutics AG (CH) | 2019-03-27 | — | — | EP | claimed |
| WO-2018113771-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION METHODS AND USES THEIROF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2018-06-28 | — | — | WO | claimed |
| WO-2017198347-A1 | TREATMENT OF SKIN LESIONS | PIQUR THERAPEUTICS AG (CH) | 2017-11-23 | — | — | WO | claimed |
| EP-2863913-A1 | IMIDAZOLYL ANALOGS AS SYK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-04-29 | — | — | EP | claimed |
| WO-2013192128-A1 | IMIDAZOLYL ANALOGS AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-12-27 | — | — | WO | claimed |
| EP-1313728-A1 | SUBSTITUTED PYRIMIDINES AS SELECTIVE CYCLOOXYGENASE-2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-05-28 | — | — | EP | claimed |
| WO-2002018374-A1 | SUBSTITUTED PYRIMIDINES AS SELECTIVE CYCLOOXYGENASE-2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2002-03-07 | — | — | WO | claimed |
| EP-0285978-A2 | Substituted 1-(2-oxyaminosulfonyl-phenylsulfonyl)-3-(4-trifluoromethyl-pyrimidin-2-yl)-(thio)-ureas | BAYER AG (DE) | 1988-10-12 | — | — | EP | claimed |
| EP-4107166-B1 | HETEROARYL COMPOUNDS FOR TREATMENT OF COMPLEMENT FACTOR D MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS INC (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-0313974-A1 | N-substituted derivatives of 1-desoxynojirimycine and 1-desoxymannonojirimycine, process for their preparation and their use as pharmaceuticals | BAYER AG (DE) | 1989-05-03 | — | — | EP | disclosed |
| EP-0285978-A2 | Substituted 1-(2-oxyaminosulfonyl-phenylsulfonyl)-3-(4-trifluoromethyl-pyrimidin-2-yl)-(thio)-ureas | BAYER AG (DE) | 1988-10-12 | — | — | EP | disclosed |