Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689233 | 0.88 | FOLH1 (0.45) | FOLH1ITGB3ITGA2BCPB2TGM2 | |
| SCHEMBL16861145 | 0.79 | FOLH1 (0.51) | FOLH1ITGB3ITGA2BCPB2TGM2 | |
| SCHEMBL29233084 | 0.79 | FOLH1 (0.51) | FOLH1ITGB3ITGA2BCPB2TGM2 | |
| SCHEMBL29233086 | 0.79 | FOLH1 (0.51) | FOLH1ITGB3ITGA2BCPB2TGM2 | |
| SCHEMBL16861144 | 0.79 | FOLH1 (0.51) | FOLH1ITGB3ITGA2BCPB2TGM2 | |
| SCHEMBL9716669 | 0.79 | FOLH1 (0.54) | FOLH1CPB2TGM2ECE1CPB1 | |
| SCHEMBL9716676 | 0.79 | FOLH1 (0.54) | FOLH1CPB2TGM2ECE1CPB1 | |
| SCHEMBL457463 | 0.78 | SLC6A5 (0.52) | FOLH1ITGB3ITGA2BTGM2SLC6A5 | |
| SCHEMBL6276612 | 0.78 | FOLH1 (0.50) | FOLH1ITGB3ITGA2BCPB2TGM2 | |
| SCHEMBL2356099 | 0.78 | SLC6A5 (0.52) | FOLH1ITGB3ITGA2BTGM2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170356023-A1 | USE OF eRF1 MUTANTS IN UNNATURAL AMINO ACID INCORPORATION | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2017-12-14 | — | — | US | disclosed |