SCHEMBL19689233

SCHEMBL19689233

CC1=CC1COC(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.45
CPB2 Q96IY4 10/20 0.42
TGM2 P21980 1/20 0.41
ECE1 P42892 1/20 0.41
CPB1 P15086 1/20 0.41
ACE P12821 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ITGB3 P05106 4/20 0.39
ITGA2B P08514 4/20 0.39
SLC6A5 Q9Y345 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19689232 0.88 FOLH1 (0.43) FOLH1CPB2TGM2ECE1CPB1
SCHEMBL31461648 0.87 CTSL (0.43) FOLH1TGM2ECE1CA2
SCHEMBL9716676 0.81 FOLH1 (0.54) FOLH1CPB2TGM2ECE1CPB1
SCHEMBL9716669 0.81 FOLH1 (0.54) FOLH1CPB2TGM2ECE1CPB1
Hydrochloric Acid SCHEMBL28265302 0.79 FOLH1 (0.53) FOLH1CPB2TGM2ECE1CPB1
SCHEMBL19689230 0.79 CPB2 (0.44) FOLH1CPB2CPB1CA1CA2
SCHEMBL9716665 0.76 FOLH1 (0.47) FOLH1CPB2TGM2ITGB3ITGA2B
SCHEMBL9716663 0.76 FOLH1 (0.47) FOLH1CPB2TGM2ITGB3ITGA2B
SCHEMBL9716671 0.76 FOLH1 (0.47) FOLH1CPB2TGM2ITGB3ITGA2B
SCHEMBL3624369 0.76 TLR2 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106164263-B Cyclopropene amino acids and methods 英国研究与创新署 2022-02-11 CN claimed
US-12378547-B2 Synthetic genome UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2025-08-05 US disclosed
WO-2025083069-A1 HER2-BINDING MOLECULES Hummingbird Bioscience Pte. Ltd. (SG) 2025-04-24 WO disclosed
WO-2025083071-A2 ANTIBODY-DRUG CONJUGATES Hummingbird Bioscience Pte. Ltd. (SG) 2025-04-24 WO disclosed
EP-3969582-A1 SYNTHETIC GENOME United Kingdom Research and Innovation (GB) 2022-03-23 EP disclosed
CN-106164263-B Cyclopropene amino acids and methods 英国研究与创新署 2022-02-11 CN disclosed
CN-107002088-B Incorporation of unnatural amino acids into proteins 英国研究与创新署 2022-01-11 CN disclosed
US-10738339-B2 Use of eRF1 mutants in unnatural amino acid incorporation UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2020-08-11 US disclosed
EP-3116993-B1 CYCLOPROPENE AMINO ACIDS AND METHODS RES & INNOVATION UK (GB) 2019-11-13 EP disclosed
EP-3212799-B1 INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS RES & INNOVATION UK (GB) 2019-04-17 EP disclosed
US-20170356023-A1 USE OF eRF1 MUTANTS IN UNNATURAL AMINO ACID INCORPORATION UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2017-12-14 US disclosed