Sugi Predict

Sugi Predict / Compounds / SCHEMBL457463

SCHEMBL457463

SCHEMBL457463

CCCCOC(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SLC6A5 Q9Y345 1/20 0.52
▸ FOLH1 Q04609 1/20 0.50
▸ NOD1 Q9Y239 4/20 0.46
▸ SIRT1 Q96EB6 3/20 0.44
▸ TLR2 O60603 3/20 0.44
▸ SIRT6 Q8N6T7 1/20 0.44
▸ ITGB3 P05106 7/20 0.43
▸ ITGA2B P08514 7/20 0.43
▸ SIRT2 Q8IXJ6 2/20 0.43
▸ SIRT3 Q9NTG7 1/20 0.43
▸ TGM2 P21980 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7534565 1.00 SLC6A5 (0.52) SLC6A5FOLH1NOD1SIRT1TLR2
SCHEMBL2356099 1.00 SLC6A5 (0.52) SLC6A5FOLH1NOD1SIRT1TLR2
SCHEMBL6688677 0.95 NOD1 (0.47) SLC6A5FOLH1NOD1ITGB3ITGA2B
SCHEMBL6688681 0.95 NOD1 (0.47) SLC6A5FOLH1NOD1ITGB3ITGA2B
SCHEMBL9716662 0.95 NOD1 (0.47) SLC6A5FOLH1NOD1ITGB3ITGA2B
SCHEMBL30915502 0.94 SLC6A5 (0.56) SLC6A5FOLH1NOD1SIRT1TLR2
SCHEMBL7804980 0.94 SLC6A5 (0.56) SLC6A5FOLH1NOD1SIRT1TLR2
SCHEMBL7797291 0.94 SLC6A5 (0.56) SLC6A5FOLH1NOD1SIRT1TLR2
SCHEMBL7803299 0.94 SLC6A5 (0.56) SLC6A5FOLH1NOD1SIRT1TLR2
SCHEMBL7804955 0.94 SLC6A5 (0.56) SLC6A5FOLH1NOD1SIRT1TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117264925-A Modified enzymes 牛津纳米孔科技公开有限公司 2023-12-22 — — CN claimed
EP-2046733-A1 PROCESS FOR THE PREPARATION OF EPSILON-ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) 2009-04-15 — — EP claimed
EP-1922345-A2 PROCESS FOR THE PREPARATION OF COPOLYMER-1 Chan, Wai Hong (US) 2008-05-21 — — EP claimed
WO-2008014811-A1 PROCESS FOR THE PREPARATION OF ε-ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) 2008-02-07 — — WO claimed
WO-2007022193-A2 PROCESS FOR THE PREPARATION OF COPOLYMER-1 CHAN WAI HONG (US) 2007-02-22 — — WO claimed
EP-1088020-A1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2001-04-04 — — EP claimed
WO-1999064495-A1 FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 — — WO claimed
US-12458685-B2 Manufacture, formulation and dosing of apraglutide VECTIVBIO AG (CH) 2025-11-04 — — US disclosed
US-20250186557-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE VECTIVBIO AG (CH) 2025-06-12 — — US disclosed
US-20250049893-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE VECTIVBIO AG (CH) 2025-02-13 — — US disclosed
US-20240325500-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE VECTIVBIO AG (CH) 2024-10-03 — — US disclosed
US-20240252595-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE VECTIVBIO AG (CH) 2024-08-01 — — US disclosed
CN-115304516-B Compounds with unconventional chromophores, their preparation and use 四川大学 2024-04-30 — — CN disclosed
US-4889869-A ANTIALDOSTERONISM AGENTS CIBA-GEIGY CORPORATION (US) 1989-12-26 — — US disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 — — US disclosed
EP-0213499-A2 Amino acid derivatives, process for their preparation and use BOEHRINGER INGELHEIM KG (DE) 1987-03-11 — — EP disclosed
EP-0203450-A2 Derivatives of bicyclic amino acids process for their preparation, agents containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1986-12-03 — — EP disclosed
EP-0090100-B1 INSOLUBLE POLYMERS WITH ANTI-COAGULATING PROPERTIES, ARTICLES CONTAINING THEM AND METHODS OF MANUFACTURE Fougnot, Christine (FR) 1986-09-17 — — EP disclosed
EP-0178911-A2 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1986-04-23 — — EP disclosed
US-3978035-A POLYPEPTIDES MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DT) 1976-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186557-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE GLP1R, IAPP, GIPR SLC6A5 2561/4885FOLH1 205/4885NOD1 1017/4885
US-20240252595-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE GLP1R, IAPP, GIPR SLC6A5 2561/4885FOLH1 205/4885NOD1 1017/4885
US-20250049893-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE GLP1R, IAPP, GIPR SLC6A5 2561/4885FOLH1 205/4885NOD1 1017/4885
US-12458685-B2 Manufacture, formulation and dosing of apraglutide GLP1R, IAPP, GIPR SLC6A5 2561/4885FOLH1 205/4885NOD1 1017/4885
US-20240325500-A1 MANUFACTURE, FORMULATION AND DOSING OF APRAGLUTIDE GLP1R, IAPP, GIPR SLC6A5 2561/4885FOLH1 205/4885NOD1 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.