SCHEMBL196908

SCHEMBL196908

O=S(=O)(O)c1cc(Br)ccc1-c1ccc(Br)cc1S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.48
BCL2 P10415 2/20 0.45
MCL1 Q07820 1/20 0.45
PTPRC P08575 1/20 0.42
CA9 Q16790 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA7 P43166 1/20 0.41
CA12 O43570 1/20 0.39
LCK P06239 1/20 0.39
METAP1 P53582 1/20 0.37
WDR5 P61964 1/20 0.37
CYP1A2 P05177 1/20 0.36
MAPK1 P28482 1/20 0.36
TGM2 P21980 1/20 0.35
CES1 P23141 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
SRD5A1 P18405 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2742903 0.88 S100A4 (0.42) S100A4BCL2MCL1PTPRCCA9
SCHEMBL1456426 0.85 PTPRC (0.43) S100A4BCL2MCL1PTPRCWDR5
SCHEMBL198694 0.82 ALDH1A1 (0.44) S100A4BCL2MCL1PTPRCCA9
SCHEMBL31357032 0.82 ALDH1A1 (0.44) S100A4BCL2MCL1PTPRCCA9
SCHEMBL2838846 0.82 S100A4 (0.48) S100A4BCL2MCL1PTPRCCA9
SCHEMBL6909032 0.80 LMNA (0.46) S100A4BCL2MCL1PTPRCCA9
SCHEMBL6914547 0.80 ALDH1A1 (0.43) S100A4BCL2MCL1PTPRCCA9
SCHEMBL6907775 0.80 ALDH1A1 (0.43) S100A4BCL2MCL1PTPRCCA9
SCHEMBL4446536 0.80 CA12 (0.38) S100A4BCL2MCL1CA9CA1
SCHEMBL6914453 0.80 ALDH1A1 (0.43) S100A4BCL2MCL1PTPRCCA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2519554-B1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING DU PONT (US) 2016-03-16 EP disclosed
US-RE45850-E1 Composition of organic compounds, optical film and method of production thereof CRYSOPTIX K.K. (JP) 2016-01-19 US disclosed
US-20150086799-A1 ORGANIC POLYMER COMPOUNDS SUITABLE FOR FORMING POSITIVE A-TYPE RETARDERS AND METHODS OF PRODUCTION THEREOF LIGHT POLYMERS HOLDING (KY) 2015-03-26 US disclosed
EP-2638126-B1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2015-02-18 EP disclosed
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-20140334002-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2014-11-13 US disclosed
EP-2390241-B1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-10-01 EP disclosed
US-8609804-B2 Polyarylene polymers and processes for preparing E I DU PONT DE NEMOURS AND COMPANY (US) 2013-12-17 US disclosed
US-8598349-B2 Method for manufacturing conjugated aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-03 US disclosed
EP-2630523-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX K.K. (JP) 2013-08-28 EP disclosed
WO-2010020928-A2 COMPOSITION OF ORGANIC COMPOUNDS, OPTICAL FILM AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2010-02-25 WO disclosed
EP-2147943-A1 CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Sumitomo Chemical Company, Limited (JP) 2010-01-27 EP disclosed
US-20090326188-A1 Method for producing polyarylene SUMITOMO CHEMICAL COMPANY, LIMITED 2009-12-31 US disclosed
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed
EP-2065420-A1 METHOD FOR PRODUCING POLYARYLENE Sumitomo Chemical Company, Limited (JP) 2009-06-03 EP disclosed
US-20090036632-A1 Polyarylene and Process for Producing the Same SUMITOMO CHEMICAL COMPANY, LIMITED 2009-02-05 US disclosed
EP-1995265-A1 POLYARYLENE AND PROCESS FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2008-11-26 EP disclosed
US-7375176-B2 Liquid crystal poly(phenylene sulfonic acids) CASE WESTERN RESERVE UNIVERSITY 2008-05-20 US disclosed
EP-1857482-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed
US-20050239994-A1 Liquid crystal poly(phenylene sulfonic acids) CASE WESTERN RESERVE UNIVERSITY 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036632-A1 Polyarylene and Process for Producing the Same CYP1A1, CYP1B1, C1R S100A4 4787/4885BCL2 420/4885MCL1 286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.