SCHEMBL1969097

SCHEMBL1969097

O=C(O)c1nccc(-c2ccccc2)n1

nearest known ligand 0.72

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMO O15229 17/20 0.72
HIF1A Q16665 1/20 0.54
AURKA O14965 1/20 0.53
HSP90AA1 P07900 1/20 0.53
PRKACA P17612 1/20 0.53
ADORA2A P29274 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27864225 0.96 KMO (0.73) KMOHIF1A
SCHEMBL3183738 0.85 MAPK8 (0.55) KMOHIF1AAURKAHSP90AA1PRKACA
SCHEMBL27986399 0.85 KMO (0.58) KMOHIF1AAURKAHSP90AA1PRKACA
SCHEMBL31301438 0.84 KMO (1.00) KMO
SCHEMBL31301427 0.84 KMO (0.71) KMO
SCHEMBL28048743 0.84 KMO (0.71) KMO
SCHEMBL3646330 0.83 KMO (0.64) KMO
SCHEMBL1669165 0.81 KDM4E (0.57) KMOHIF1AHSP90AA1
SCHEMBL30037083 0.81 KDM4E (0.57) KMOHIF1AHSP90AA1
SCHEMBL30489168 0.81 MEN1 (0.69) KMOHIF1AAURKAHSP90AA1PRKACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5112523-A High clearing point for liquid crystal displays CHISSO CORPORATION (JP) 1992-05-12 US claimed
US-4874546-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1989-10-17 US claimed
EP-3810596-B1 QUINOLINE DERIVATIVES USEFUL AS TYROSINE KINASE INHIBITORS RIGEL PHARMACEUTICALS INC (US) 2022-11-30 EP disclosed
US-11390589-B2 Herbicidally active substituted phenylpyrimidines BAYER AKTIENGESELLSCHAFT (DE) 2022-07-19 US disclosed
WO-2022137033-A1 ORGANIC METAL COMPLEX, LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC EQUIPMENT, AND ILLUMINATION APPARATUS 株式会社半導体エネルギー研究所 2022-06-30 WO disclosed
WO-2022137023-A1 LIGHT EMISSION DEVICE, LIGHT EMISSION APPARATUS, ELECTRONIC EQUIPMENT, AND ILLUMINATION DEVICE 株式会社半導体エネルギー研究所 2022-06-30 WO disclosed
WO-2022130107-A1 LIGHT EMITTING DEVICE, LIGHT EMITTING APPARATUS, ELECTRONIC DEVICE AND LIGHTING DEVICE 株式会社半導体エネルギー研究所 2022-06-23 WO disclosed
WO-2022090863-A1 ORGANIC COMPOUND, CARRIER TRANSPORT MATERIAL, HOST MATERIAL, LIGHT EMITTING DEVICE, LIGHT EMITTING APPARATUS, ELECTRONIC EQUIPMENT, AND LIGHTING APPARATUS 株式会社半導体エネルギー研究所 2022-05-05 WO disclosed
WO-2022074499-A1 LIGHT-EMITTING APPARATUS, ELECTRONIC EQUIPMENT, AND ILLUMINATION APPARATUS 株式会社半導体エネルギー研究所 2022-04-14 WO disclosed
WO-2022053905-A1 ORGANIC METAL COMPLEX, LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC EQUIPMENT, AND LIGHTING DEVICE 株式会社半導体エネルギー研究所 2022-03-17 WO disclosed
WO-2022023864-A1 LIGHT EMITTING DEVICE, LIGHT EMITTING APPARATUS, LIGHT EMITTING MODULE, ELECTRONIC DEVICE AND LIGHTING DEVICE 株式会社半導体エネルギー研究所 2022-02-03 WO disclosed
EP-2334643-A1 PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES Actelion Pharmaceuticals Ltd. (CH) 2011-06-22 EP disclosed
WO-2010044054-A1 PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES ACTELION PHARMACEUTICALS LTD (CH) 2010-04-22 WO disclosed
US-7485647-B2 2-aminoquinoline derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2009-02-03 US disclosed
US-20060287340-A1 2-Aminoquinoline derivatives MSD K.K. (JP) 2006-12-21 US disclosed
EP-1630162-A1 2-AMINOQUINOLINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-03-01 EP disclosed
US-5112523-A High clearing point for liquid crystal displays CHISSO CORPORATION (JP) 1992-05-12 US disclosed
US-5112523-A High clearing point for liquid crystal displays CHISSO CORPORATION (JP) 1992-05-12 US disclosed
US-4874546-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1989-10-17 US disclosed
US-4874546-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1989-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287340-A1 2-Aminoquinoline derivatives MCHR2, MC2R, MCHR1 KMO 285/4885HIF1A 1014/4885AURKA 2395/4885
US-11390589-B2 Herbicidally active substituted phenylpyrimidines DDT, DPYD, GSTP1 KMO 1563/4885HIF1A 2571/4885AURKA 3058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.