Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 18/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301427 | 1.00 | KMO (0.71) | KMOSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28048742 | 0.85 | KMO (0.55) | KMOSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28048792 | 0.85 | MEN1 (0.53) | KMOSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27864225 | 0.84 | KMO (0.73) | KMO | |
| SCHEMBL1969097 | 0.84 | KMO (0.72) | KMO | |
| SCHEMBL31301438 | 0.83 | KMO (1.00) | KMOMEN1KMT2A | |
| SCHEMBL31301500 | 0.82 | KMO (0.69) | KMO | |
| SCHEMBL31301481 | 0.82 | KMO (0.65) | KMOSMN1; SMN2 | |
| SCHEMBL4901594 | 0.80 | MEN1 (0.69) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4897772 | 0.80 | MEN1 (0.69) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732616-B | Pyrrolopyridines of the amide structure containing biaryl and its preparation method and application | 江西科技师范大学 | 2018-07-27 | — | — | CN | disclosed |
| CN-105153026-B | Sorafenib derivative of the amide structure containing biaryl and its preparation method and application | 江西科技师范大学 | 2018-02-02 | — | — | CN | disclosed |
| CN-105732616-A | Pyrrolopyridine compounds containing biaryl amide structure, preparation method and applications thereof | 江西科技师范大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-105153026-A | Biaryl amide structure containing sorafenib derivative as well as preparation method and applications thereof | UNIV JIANGXI NORMAL SCI & TECH | 2015-12-16 | — | — | CN | disclosed |