SCHEMBL19692309

SCHEMBL19692309

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@](O)(C(=O)NCCN)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.60
CYP46A1 Q9Y6A2 2/20 0.60
LMNA P02545 1/20 0.60
ABCB1 P08183 1/20 0.60
OSBP P22059 1/20 0.60
RORC P51449 1/20 0.60
OSBP2 Q969R2 1/20 0.60
POLA1 P09884 1/20 0.57
GRIN1 Q05586 12/20 0.56
GRIN2B Q13224 12/20 0.56
GRIN2A Q12879 10/20 0.55
SRD5A1 P18405 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL998341 1.00 USP2 (0.60) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL19691912 0.92 USP2 (0.60) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL3359948 0.92 USP2 (0.60) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL1050027 0.91 USP2 (0.59) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL22658123 0.91 USP2 (0.59) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL8205164 0.91 USP2 (0.59) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL1081197 0.91 USP2 (0.59) USP2CYP46A1LMNAABCB1OSBP
Hydrochloric Acid SCHEMBL11907786 0.91 USP2 (0.58) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL18797660 0.91 USP2 (0.58) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2440566 0.91 OSBP (0.58) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3357491-B1 PHARMACEUTICAL COMPOSITION FOR DELIVERING AN ANIONIC DRUG SAMYANG BIOPHARMACEUTICALS (KR) 2021-06-02 EP claimed
EP-2833869-B1 METHOD OF PREPARING COMPOSITION FOR DELIVERING AN ANIONIC DRUG SAMYANG BIOPHARMACEUTICALS (KR) 2020-10-28 EP claimed
US-20190336611-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CUREVAC AG (DE) 2019-11-07 US claimed
EP-3468608-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac AG (DE) 2019-04-17 EP claimed
EP-3468612-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac AG (DE) 2019-04-17 EP claimed
EP-2217221-B1 LDL-LIKE CATIONIC NANOPARTICLES FOR DELIVERYING NUCLEIC ACID GENE, METHOD FOR PREPARING THEREOF AND METHOD FOR DELIVERYING NUCLEIC ACID GENE USING THE SAME KOREA ADVANCED INST SCI & TECH (KR) 2018-06-27 EP claimed
WO-2017212008-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CUREVAC AG (DE) 2017-12-14 WO claimed
WO-2017212006-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CUREVAC AG (DE) 2017-12-14 WO claimed
CN-117462515-A Kit for rapidly preparing lipid nucleic acid nano-drug and preparation method thereof 上海镁纳生物科技有限公司 2024-01-30 CN disclosed
CN-117377467-A Kit for preparing drug-containing and amphiphilic polymer-free nanoparticles 三养控股公司 2024-01-09 CN disclosed
CN-117241791-A Composition for drug delivery comprising nanoparticles free of amphiphilic polymer 三养控股公司 2023-12-15 CN disclosed
WO-2023147552-A1 RADIOSENSITIZING COMPOSITIONS AND METHODS OF USE THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2023-08-03 WO disclosed
WO-2021125805-A1 KIT FOR PREPARING NANOPARTICLE COMPOSITION FOR DRUG DELIVERY, COMPRISING POLYLACTIC ACID SALT 주식회사 삼양홀딩스 2021-06-24 WO disclosed
EP-3695850-A1 CARRIER FOR NEGATIVELY CHARGED DRUGS COMPRISING A CATIONIC LIPID AND A PREPARATION METHOD THEREOF Samyang Biopharmaceuticals Corporation (KR) 2020-08-19 EP disclosed
WO-2019098691-A9 COMPOSITION AND METHOD FOR FREEZE-DRYING PHARMACEUTICAL COMPOSITION CONTAINING ANIONIC DRUG 주식회사 삼양바이오팜 2019-08-29 WO disclosed
EP-3468608-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac AG (DE) 2019-04-17 EP disclosed
EP-3468612-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac AG (DE) 2019-04-17 EP disclosed
EP-3391875-A1 METHOD FOR PREPARING POLYMERIC MICELLE CONTAINING ANIONIC DRUG Samyang Biopharmaceuticals Corporation (KR) 2018-10-24 EP disclosed
WO-2017212006-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CUREVAC AG (DE) 2017-12-14 WO disclosed
WO-2017212008-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CUREVAC AG (DE) 2017-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190336611-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO PHAX, LNPEP, PITPNB USP2 3765/4885CYP46A1 766/4885LMNA 278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.