SCHEMBL998341

SCHEMBL998341

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@](O)(C(=O)NCCN)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.60
CYP46A1 Q9Y6A2 2/20 0.60
LMNA P02545 1/20 0.60
ABCB1 P08183 1/20 0.60
OSBP P22059 1/20 0.60
RORC P51449 1/20 0.60
OSBP2 Q969R2 1/20 0.60
POLA1 P09884 1/20 0.57
GRIN1 Q05586 12/20 0.56
GRIN2B Q13224 12/20 0.56
GRIN2A Q12879 10/20 0.55
SRD5A1 P18405 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19692309 1.00 USP2 (0.60) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL19691912 0.92 USP2 (0.60) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL3359948 0.92 USP2 (0.60) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL1050027 0.91 USP2 (0.59) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL22658123 0.91 USP2 (0.59) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL8205164 0.91 USP2 (0.59) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL1081197 0.91 USP2 (0.59) USP2CYP46A1LMNAABCB1OSBP
Hydrochloric Acid SCHEMBL11907786 0.91 USP2 (0.58) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL18797660 0.91 USP2 (0.58) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2440566 0.91 OSBP (0.58) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022255701-A1 LIPOPROTEIN-MIMICKING SOLID LIPID NANOPARTICLES FOR DRUG DELIVERY AND USES THEREOF 주식회사 티온랩테라퓨틱스 2022-12-08 WO claimed
EP-3357491-B1 PHARMACEUTICAL COMPOSITION FOR DELIVERING AN ANIONIC DRUG SAMYANG BIOPHARMACEUTICALS (KR) 2021-06-02 EP claimed
US-20210077406-A1 COMPOSITION AND METHOD FOR FREEZE-DRYING PHARMACEUTICAL COMPOSITION CONTAINING ANIONIC DRUG SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) 2021-03-18 US claimed
EP-2833869-B1 METHOD OF PREPARING COMPOSITION FOR DELIVERING AN ANIONIC DRUG SAMYANG BIOPHARMACEUTICALS (KR) 2020-10-28 EP claimed
US-10292932-B2 Polymeric micelle particle comprising anionic drugs and method of preparing the same SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) 2019-05-21 US claimed
US-20180250409-A1 PHARMACEUTICAL COMPOSITION CONTAINING ANIONIC DRUG, AND PREPARATION METHOD THEREFOR SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) 2018-09-06 US claimed
EP-3357491-A1 PHARMACEUTICAL COMPOSITION CONTAINING ANIONIC DRUG, AND PREPARATION METHOD THEREFOR Samyang Biopharmaceuticals Corporation (KR) 2018-08-08 EP claimed
EP-2217221-B1 LDL-LIKE CATIONIC NANOPARTICLES FOR DELIVERYING NUCLEIC ACID GENE, METHOD FOR PREPARING THEREOF AND METHOD FOR DELIVERYING NUCLEIC ACID GENE USING THE SAME KOREA ADVANCED INST SCI & TECH (KR) 2018-06-27 EP claimed
US-10004694-B2 Targeted poorly water-soluble drug delivery system, method of preparing the same, and pharmaceutical composition including the same SAMSUNG LIFE PUBLIC WELFARE FOUNDATION (KR) 2018-06-26 US claimed
US-9439856-B2 Method of preparing composition for delivering an anionic drug SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) 2016-09-13 US claimed
US-9439858-B2 Temperature sensitive liposome including cationic lipid and use thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-09-13 US claimed
US-20160228361-A1 POLYMERIC MICELLE PARTICLE COMPRISING ANIONIC DRUGS AND METHOD OF PREPARING THE SAME SAMYANG HOLDINGS CORPORATION (KR) 2016-08-11 US claimed
US-20150328152-A1 Method of Preparing Composition for Delivering an Anionic Drug SAMYANG HOLDINGS CORPORATION (KR) 2015-11-19 US claimed
US-20150297749-A1 LOW-DENSITY LIPOPROTEIN ANALOGUE NANOPARTICLES, AND COMPOSITION COMPRISING SAME FOR TARGETED DIAGNOSIS AND TREATMENT OF LIVER POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2015-10-22 US claimed
US-20110268772-A1 PHARMACEUTICAL COMPOSITION CONTAINING AN ANIONIC DRUG AND A PRODUCTION METHOD THEREOF SAMYANG CORPORATION (KR) 2011-11-03 US claimed
EP-2377517-A2 PHARMACEUTICAL COMPOSITION CONTAINING AN ANIONIC DRUG, AND A PRODUCTION METHOD THEREFOR Samyang Corporation (KR) 2011-10-19 EP claimed
JP-2011500671-A 2011-01-06 JP claimed
US-20100297242-A1 LDL-LIKE CATIONIC NANOPARTICLES FOR DELIVERYING NUCLEIC ACID GENE, METHOD FOR PREPARING THEREOF AND METHOD FOR DELIVERYING NUCLEIC ACID GENE USING THE SAME SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) 2010-11-25 US claimed
EP-2217221-A2 LDL-LIKE CATIONIC NANOPARTICLES FOR DELIVERYING NUCLEIC ACID GENE, METHOD FOR PREPARING THEREOF AND METHOD FOR DELIVERYING NUCLEIC ACID GENE USING THE SAME Korea Advanced Institute of Science and Technology (KR) 2010-08-18 EP claimed
WO-2009051451-A2 LDL-LIKE CATIONIC NANOPARTICLES FOR DELIVERYING NUCLEIC ACID GENE, METHOD FOR PREPARING THEREOF AND METHOD FOR DELIVERYING NUCLEIC ACID GENE USING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-04-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210077406-A1 COMPOSITION AND METHOD FOR FREEZE-DRYING PHARMACEUTICAL COMPOSITION CONTAINING ANIONIC DRUG ANXA6, PHOSPHO1, ABHD16A USP2 2958/4885CYP46A1 1509/4885LMNA 3154/4885
US-10004694-B2 Targeted poorly water-soluble drug delivery system, method of preparing the same, and pharmaceutical composition including the same CD44, TP53, ASGR1 USP2 495/4885CYP46A1 891/4885LMNA 4255/4885
US-20150328152-A1 Method of Preparing Composition for Delivering an Anionic Drug LIPA, APOB, CETP USP2 3027/4885CYP46A1 102/4885LMNA 216/4885
US-20180250409-A1 PHARMACEUTICAL COMPOSITION CONTAINING ANIONIC DRUG, AND PREPARATION METHOD THEREFOR THEM6, NOTUM, CETP USP2 4415/4885CYP46A1 32/4885LMNA 1750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.