SCHEMBL196945

SCHEMBL196945

CCOS(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
MAPK1 P28482 2/20 0.48
CYP3A4 P08684 1/20 0.48
POLB P06746 2/20 0.46
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
CA12 O43570 3/20 0.45
CA3 P07451 3/20 0.45
CA4 P22748 3/20 0.45
CA6 P23280 3/20 0.45
CA5A P35218 3/20 0.45
CA7 P43166 3/20 0.45
CA9 Q16790 3/20 0.45
CA13 Q8N1Q1 3/20 0.45
CA14 Q9ULX7 3/20 0.45
CA5B Q9Y2D0 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MMP1 P03956 1/20 0.45
MMP2 P08253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27670058 0.84 ALDH1A1 (0.45) ALDH1A1MAPK1CYP3A4POLBCA1
SCHEMBL27890927 0.83 ALDH1A1 (0.42) ALDH1A1MAPK1CYP3A4POLBCA1
SCHEMBL196957 0.83 SMN1; SMN2 (0.47) ALDH1A1MAPK1CA1CA2CA12
SCHEMBL6115151 0.83 ALDH1A1 (0.52) ALDH1A1MAPK1CYP3A4CA1CA2
SCHEMBL27649743 0.81 CA2 (0.46) ALDH1A1MAPK1CYP3A4POLBCA1
SCHEMBL76249 0.81 GAA (0.50) ALDH1A1CYP3A4CA1CA2CA12
SCHEMBL28996978 0.81 ENPP2 (0.46) CA1CA2CA12CA7CA9
SCHEMBL552333 0.81 GAA (0.57) ALDH1A1CYP3A4CA1CA2CA12
SCHEMBL11888429 0.80 GAA (0.43) ALDH1A1MAPK1POLBCA1CA2
SCHEMBL4192257 0.80 RECQL (0.46) ALDH1A1MAPK1CYP3A4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116621873-A Method for preparing ethyl methyl ethyl phosphinate and aluminum methyl ethyl phosphinate 福华通达化学股份公司 2023-08-22 CN claimed
CN-113582935-A Inflammatory corpuscle nucleotide-binding oligomerization domain-like receptor protein 3 inhibitor and preparation method and application thereof 中国医学科学院放射医学研究所 2021-11-02 CN claimed
EP-4720078-A1 FLAME-RETARDANT POLYURETHANE AND USES THEREOF Clariant International Ltd (CH) 2026-04-08 EP disclosed
WO-2024239791-A1 FLAME-RETARDANT POLYURETHANE AND USES THEREOF CLARIANT INTERNATIONAL LTD (CH) 2024-11-28 WO disclosed
CN-118715015-A Selective PHD1 inhibitor compounds, compositions and methods of use 阿克比治疗有限公司 2024-09-27 CN disclosed
CN-116621873-A Method for preparing ethyl methyl ethyl phosphinate and aluminum methyl ethyl phosphinate 福华通达化学股份公司 2023-08-22 CN disclosed
CN-113582935-A Inflammatory corpuscle nucleotide-binding oligomerization domain-like receptor protein 3 inhibitor and preparation method and application thereof 中国医学科学院放射医学研究所 2021-11-02 CN disclosed
EP-2791094-B1 A PROCESS FOR MANUFACTURING HALOARYL COMPOUNDS FROM MIXTURES OF ISOMERS OF DIHALODIARYLSULFONES SOLVAY SPECIALTY POLYMERS USA (US) 2021-02-17 EP disclosed
EP-2827433-B1 SECONDARY BATTERY ELECTROLYTE AND SECONDARY BATTERY USING SAME ENVISION AESC ENERGY DEVICES LTD (JP) 2019-09-25 EP disclosed
CN-109369468-A For the method from the mixture of dihalo- diaryl sulfone isomers manufacture halogen aryl compound 索尔维特殊聚合物美国有限责任公司 2019-02-22 CN disclosed
CN-106966855-A Method for manufacturing halogen aryl compound from the mixture of dihalo- diaryl sulfone isomers 索尔维特殊聚合物美国有限责任公司 2017-07-21 CN disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
CN-100381421-C Process for producing triarylsulfonium salt WAKO PURE CHEM IND LTD (JP) 2008-04-16 CN disclosed
CN-1871212-A Process for producing triarylsulfonium salt WAKO PURE CHEM IND LTD (JP) 2006-11-29 CN disclosed
WO-2002060374-A2 BENZ-1,3-AZOLE DERIVATIVES AND THEIR USES AS HEPARANASE INHIBITORS INSIGHT STRATEGY AND MARKETING LTD (IL) 2002-08-08 WO disclosed
EP-0115328-B1 PROCESS FOR THE PREPARATION OF 4-CHLORO-PHENYL-SULPHONYL-COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1986-02-19 EP disclosed
EP-0115328-A1 Process for the preparation of 4-chloro-phenyl-sulphonyl-compounds HOECHST AKTIENGESELLSCHAFT (DE) 1984-08-08 EP disclosed
EP-0023652-B1 PROCESS FOR THE PREPARATION OF CATIONIC DYESTUFFS BAYER AG (DE) 1984-05-09 EP disclosed
US-4349670-A Process for the preparation of cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1982-09-14 US disclosed
EP-0023652-A1 Process for the preparation of cationic dyestuffs BAYER AG (DE) 1981-02-11 EP disclosed