Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.37 |
| ▸ | DPP4 | P27487 | 5/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19695525 | 0.95 | RAB9A (0.43) | RAB9ANOTUMDPP9POLBMAOB | |
| SCHEMBL19695512 | 0.83 | MAOB (0.46) | RAB9ANOTUMDPP9AKR1C3MAOB | |
| SCHEMBL19690561 | 0.79 | KCNQ2 (0.41) | RAB9ANOTUMDPP9AKR1C3DPP8 | |
| SCHEMBL19695514 | 0.78 | MAOB (0.46) | RAB9ANOTUMDPP9MAOBDPP8 | |
| SCHEMBL19695407 | 0.77 | DPP7 (0.39) | NOTUMDPP4DPP7MAPTCYP3A4 | |
| SCHEMBL19690481 | 0.76 | RAB9A (0.56) | RAB9APOLBMAPT | |
| SCHEMBL30741294 | 0.75 | KCNQ2 (0.50) | RAB9ANOTUMKCNQ2CYP3A4 | |
| SCHEMBL19698500 | 0.75 | KCNQ2 (0.50) | RAB9ANOTUMKCNQ2CYP3A4 | |
| SCHEMBL19690479 | 0.74 | KCNQ2 (0.45) | RAB9ANOTUMDPP9DPP8DPP4 | |
| SCHEMBL19698503 | 0.73 | KCNQ2 (0.45) | RAB9ANOTUMDPP9DPP8DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468947-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SciFluor Life Sciences, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017214539-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-12-14 | — | — | WO | disclosed |