Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19690462 | 0.79 | L3MBTL1 (0.40) | DPP7NOTUMKIF11MAPTNAMPT | |
| SCHEMBL19695401 | 0.77 | RAB9A (0.43) | DPP7NOTUMCYP3A4MAPTDPP4 | |
| SCHEMBL19695525 | 0.77 | RAB9A (0.43) | DPP7NOTUMCYP3A4MAPTDPP4 | |
| SCHEMBL19695405 | 0.76 | KIF11 (0.37) | NOTUMKIF11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19690305 | 0.76 | MAPT (0.45) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL19695520 | 0.76 | LMNA (0.39) | DPP7NOTUMKIF11MAPTALDH1A1 | |
| SCHEMBL19695491 | 0.76 | LMNA (0.39) | DPP7NOTUMKIF11MAPTALDH1A1 | |
| SCHEMBL19698452 | 0.75 | KCNQ2 (0.56) | DPP7CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL30741260 | 0.75 | KCNQ2 (0.56) | DPP7CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL19690590 | 0.71 | NOTUM (0.41) | DPP7NOTUMMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468947-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SciFluor Life Sciences, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017214539-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-12-14 | — | — | WO | disclosed |