Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.38 |
| ▸ | DPP4 | P27487 | 5/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19695514 | 0.95 | MAOB (0.46) | MAOBKCNQ2DPP9NR3C2DPP8 | |
| SCHEMBL19695491 | 0.85 | LMNA (0.39) | MAOBDPP7NOTUM | |
| SCHEMBL19695401 | 0.83 | RAB9A (0.43) | MAOBKCNQ2DPP9AKR1C3DPP8 | |
| SCHEMBL19695520 | 0.81 | LMNA (0.39) | MAOBDPP7NOTUM | |
| SCHEMBL19695525 | 0.78 | RAB9A (0.43) | MAOBKCNQ2DPP9DPP8DPP4 | |
| SCHEMBL19690466 | 0.77 | HDAC3 (0.49) | MAOBKCNQ2DPP9NR3C2AKR1C3 | |
| SCHEMBL27580041 | 0.75 | KEAP1 (0.44) | RAB9A | |
| SCHEMBL19690301 | 0.74 | LMNA (0.58) | MAOBKCNQ2NR3C2RAB9A | |
| SCHEMBL30741267 | 0.73 | KCNQ2 (0.50) | MAOBKCNQ2 | |
| SCHEMBL19698755 | 0.73 | KCNQ2 (0.50) | MAOBKCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468947-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SciFluor Life Sciences, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017214539-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-12-14 | — | — | WO | disclosed |