Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.65 |
| ▸ | MEN1 | O00255 | 9/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | GAA | P10253 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1900840 | 0.90 | KMT2A (0.68) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL1900841 | 0.90 | KMT2A (0.68) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL17498778 | 0.81 | HDAC1 (0.55) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL9607124 | 0.80 | KMT2A (0.57) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL6936350 | 0.76 | RAB9A (0.78) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL7105109 | 0.76 | RAB9A (0.78) | KMT2AMEN1MAPTNPC1RAB9A | |
| Vanillin SCHEMBL28367299 | 0.76 | ALDH1A1 (0.58) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL28465286 | 0.76 | KMT2A (1.00) | KMT2AMEN1MAPTNPC1RAB9A | |
| Curcumin SCHEMBL12988139 | 0.75 | APP (0.64) | KMT2AMEN1MAPTKDM4EGAA | |
| SCHEMBL28471161 | 0.74 | MEN1 (0.48) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839640-B2 | Methods of treating eye diseases associated with inflammation and vascular proliferation | OCCURX PTY LTD (AU) | 2017-12-12 | — | — | US | disclosed |