Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950480 | 0.91 | LTB4R (0.61) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL13002056 | 0.87 | LTB4R (0.55) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL15396460 | 0.84 | LTB4R (0.53) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL9607122 | 0.82 | LTB4R (0.52) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL19695909 | 0.82 | LTB4R (0.52) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL19695907 | 0.82 | LTB4R (0.52) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL9607118 | 0.82 | LTB4R (0.52) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL15396459 | 0.81 | LTB4R (0.47) | LTB4RDEGS1ALDH1A1NPC1HTT | |
| SCHEMBL2947337 | 0.80 | LTB4R (0.48) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL9607119 | 0.80 | LTB4R (0.48) | LTB4RCHEK1PIM1MAPK8CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839640-B2 | Methods of treating eye diseases associated with inflammation and vascular proliferation | OCCURX PTY LTD (AU) | 2017-12-12 | — | — | US | disclosed |