Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19695945 | 0.91 | LTB4R (0.56) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL13002056 | 0.89 | LTB4R (0.55) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL9607118 | 0.88 | LTB4R (0.52) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL19695909 | 0.88 | LTB4R (0.52) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL19695907 | 0.88 | LTB4R (0.52) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL9607122 | 0.88 | LTB4R (0.52) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL15396460 | 0.86 | LTB4R (0.53) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL21024669 | 0.84 | LTB4R (0.57) | LTB4RALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2947337 | 0.84 | LTB4R (0.48) | LTB4RCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL9607119 | 0.84 | LTB4R (0.48) | LTB4RCHEK1PIM1MAPK8CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485883-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | OccuRx Pty Ltd (AU) | 2019-05-22 | — | — | EP | disclosed |
| WO-2010144959-A1 | ANALOGUES OF ANTI-FIBROTIC AGENTS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010144959-A1 | ANALOGUES OF ANTI-FIBROTIC AGENTS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2010-12-23 | — | — | WO | disclosed |