Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.34 |
| ▸ | THRA | P10827 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TTR | P02766 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584522 | 0.95 | SMN1; SMN2 (0.36) | THRBTHRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12837222 | 0.86 | EPHX2 (0.42) | THRBTHRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19696689 | 0.85 | THRB (0.35) | THRBTHRACNR1CNR2PPARG | |
| SCHEMBL12584523 | 0.82 | THRB (0.36) | THRBTHRASMN1; SMN2PPARGRXRA | |
| SCHEMBL1525943 | 0.81 | EPHX2 (0.42) | THRBTHRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14239796 | 0.79 | MGLL (0.43) | THRBTHRASMN1; SMN2PPARGRXRA | |
| SCHEMBL15942568 | 0.77 | — | — | |
| SCHEMBL12837225 | 0.77 | THRB (0.56) | THRBTHRASMN1; SMN2PPARGRXRA | |
| SCHEMBL12837226 | 0.74 | THRB (0.52) | THRBTHRANPC1RAB9APPARG | |
| SCHEMBL12837224 | 0.74 | EPHX2 (0.43) | THRBTHRANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839614-B2 | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof | NANOPHARMACEUTICALS, LLC (US) | 2017-12-12 | — | — | US | disclosed |