Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PCNA | P12004 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525943 | 0.94 | EPHX2 (0.42) | EPHX2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL12837226 | 0.87 | THRB (0.52) | EPHX2MEN1KMT2ALMNATHRA | |
| SCHEMBL19696711 | 0.86 | THRB (0.34) | EPHX2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL12837224 | 0.86 | EPHX2 (0.43) | EPHX2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14239795 | 0.85 | THRB (0.50) | EPHX2MEN1KMT2ALMNATHRA | |
| SCHEMBL12837225 | 0.84 | THRB (0.56) | MEN1KMT2ALMNASMN1; SMN2THRA | |
| SCHEMBL14239796 | 0.82 | MGLL (0.43) | MEN1KMT2ALMNASMN1; SMN2THRA | |
| SCHEMBL17365412 | 0.81 | THRB (0.55) | EPHX2MEN1KMT2ALMNATHRA | |
| SCHEMBL1526151 | 0.80 | THRB (0.60) | EPHX2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL12584522 | 0.80 | SMN1; SMN2 (0.36) | EPHX2MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110052715-A1 | NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE ANALOGS, ANTAGONISTS, AND FORMULATIONS AND USES THEREOF | NANOPHARMACEUTICALS LLC | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052715-A1 | NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE ANALOGS, ANTAGONISTS, AND FORMULATIONS AND USES THEREOF | TSHR, THRA, TRHR | EPHX2 2794/4885MEN1 405/4885KMT2A 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.