Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25887996 | 0.80 | ALDH1A1 (0.45) | ALDH1A1GRIK1GRM8GRM6GRIN2D | |
| SCHEMBL16020420 | 0.80 | ALDH1A1 (0.45) | ALDH1A1GRIK1GRM8GRM6GRIN2D | |
| SCHEMBL14273882 | 0.80 | ALDH1A1 (0.45) | ALDH1A1GRIK1GRM8GRM6GRIN2D | |
| SCHEMBL27349738 | 0.80 | GSR (0.42) | GRIK1GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL27349737 | 0.80 | GSR (0.42) | GRIK1GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL3870432 | 0.78 | KMT2A (0.44) | ALDH1A1GRIK1GRM8GRM6GRIN2D | |
| SCHEMBL20107051 | 0.78 | KMT2A (0.44) | ALDH1A1GRIK1GRM8GRM6GRIN2D | |
| SCHEMBL3867126 | 0.78 | GSR (0.65) | ALDH1A1GRIK1GRM8GRM6GRIN2D | |
| SCHEMBL1330943 | 0.78 | GSR (0.65) | ALDH1A1GRIK1GRM8GRM6GRIN2D | |
| SCHEMBL15871922 | 0.78 | CYP1A2 (0.65) | GRIK1GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839694-B2 | Reduction of endotoxins from polyanionic polymer conjugates | NITTO DENKO CORPORATION (JP) | 2017-12-12 | — | — | US | disclosed |