Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27349738 | 1.00 | GSR (0.42) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL15871922 | 0.82 | CYP1A2 (0.65) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL19696723 | 0.80 | ALDH1A1 (0.41) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL15582587 | 0.80 | GRIK1 (0.39) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL16272838 | 0.76 | — | — | |
| SCHEMBL29803185 | 0.76 | — | — | |
| SCHEMBL30759481 | 0.74 | — | — | |
| SCHEMBL27960277 | 0.72 | FAAH (0.42) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL31036833 | 0.72 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1GABRPGABRD | |
| SCHEMBL28486930 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057653-A | Be used for the treatment of the glutamic acid difluoride of tumour and the binding substances of folacin compound and antifol | HEALTH RESEARCH INC (US) | 1992-01-08 | — | — | CN | disclosed |
| CN-1057653-A | Be used for the treatment of the glutamic acid difluoride of tumour and the binding substances of folacin compound and antifol | HEALTH RESEARCH INC (US) | 1992-01-08 | — | — | CN | disclosed |
| CN-1057653-A | Be used for the treatment of the glutamic acid difluoride of tumour and the binding substances of folacin compound and antifol | HEALTH RESEARCH INC (US) | 1992-01-08 | — | — | CN | disclosed |
| CN-1055740-A | The glutamic acid difluoride and folic acid and the antifolic conjugates that are used for the treatment of tumor disease | MERRELL DOW PHARMA (US) | 1991-10-30 | — | — | CN | disclosed |
| CN-1055740-A | The glutamic acid difluoride and folic acid and the antifolic conjugates that are used for the treatment of tumor disease | MERRELL DOW PHARMA (US) | 1991-10-30 | — | — | CN | disclosed |
| CN-1055740-A | The glutamic acid difluoride and folic acid and the antifolic conjugates that are used for the treatment of tumor disease | MERRELL DOW PHARMA (US) | 1991-10-30 | — | — | CN | disclosed |