Sugi Predict

Sugi Predict / Compounds / SCHEMBL3870432

SCHEMBL3870432

SCHEMBL3870432

CC(=O)CCC(N)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.44
▸ BLM P54132 2/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ PMP22 Q01453 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.43
▸ CYP1A2 P05177 2/20 0.41
▸ GRM8 O00222 1/20 0.41
▸ GRM6 O15303 1/20 0.41
▸ GRIN2D O15399 1/20 0.41
▸ GRIN3B O60391 1/20 0.41
▸ GSR P00390 1/20 0.41
▸ GRIK1 P39086 1/20 0.41
▸ GRM5 P41594 1/20 0.41
▸ GRIA1 P42261 1/20 0.41
▸ GRIA2 P42262 1/20 0.41
▸ GRIA3 P42263 1/20 0.41
▸ SLC1A3 P43003 1/20 0.41
▸ SLC1A2 P43004 1/20 0.41
▸ SLC1A1 P43005 1/20 0.41
▸ GRIA4 P48058 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20107051 1.00 KMT2A (0.44) KMT2ABLMALOX15PMP22ALDH1A1
SCHEMBL24016432 0.84 PAOX (0.46) KMT2ABLMALOX15PMP22ALDH1A1
SCHEMBL556329 0.82 PAOX (0.50) KMT2ABLMALDH1A1CYP1A2GSR
SCHEMBL25887996 0.82 ALDH1A1 (0.45) KMT2ABLMALOX15PMP22ALDH1A1
SCHEMBL14273882 0.82 ALDH1A1 (0.45) KMT2ABLMALOX15PMP22ALDH1A1
SCHEMBL16020420 0.82 ALDH1A1 (0.45) KMT2ABLMALOX15PMP22ALDH1A1
Acetic Acid SCHEMBL11293830 0.81 CYP1A2 (0.60) KMT2ABLMALOX15PMP22CYP1A2
SCHEMBL20987558 0.81 KMT2A (0.41) KMT2ABLMALOX15PMP22ALDH1A1
Acetic Acid SCHEMBL8584855 0.81 CYP1A2 (0.60) KMT2ABLMALOX15PMP22CYP1A2
SCHEMBL3867126 0.80 GSR (0.65) KMT2ABLMALOX15PMP22ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100580087-C Conjugation of peptides NOVO NORDISK HEALTHCARE AG 2010-01-13 — — CN claimed
US-20090253166-A1 Conjugation of Peptides NOVO NORDISK A/S (DK) 2009-10-08 — — US claimed
US-20090105134-A1 C-Terminally Pegylated Growth Hormones NOVO NORDISK A/S (DK) 2009-04-23 — — US claimed
JP-2008531482-A — — 2008-08-14 — — JP claimed
EP-1850878-A2 C-TERMINALLY PEGYLATED GROWTH HORMONES NOVO NORDISK A/S (DK) 2007-11-07 — — EP claimed
US-20070111926-A1 Conjugation of peptides NOVO NORDISK A/S (DK) 2007-05-17 — — US claimed
CN-1863920-A Conjugation of peptides NOVO NORDISK AS (DK) 2006-11-15 — — CN claimed
WO-2006084888-A2 C-TERMINALLY PEGYLATED GROWTH HORMONES NOVO NORDISK A/S (DK) 2006-08-17 — — WO claimed
EP-1673464-A2 CONJUGATION OF PEPTIDES NOVO NORDISK A/S (DK) 2006-06-28 — — EP claimed
WO-2005035553-A2 CONJUGATION OF PEPTIDES NOVO NORDISK A/S (DK) 2005-04-21 — — WO claimed
US-11813334-B2 Polyethylene glycol conjugate drug, and preparation method therefor and use thereof Chongqing Upgra Biotechnology Co., Ltd. (CN) 2023-11-14 — — US disclosed
EP-3689868-B1 TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS ARVINAS OPERATIONS INC (US) 2023-09-27 — — EP disclosed
US-20230277677-A1 POLYMERIC CONJUGATES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-09-07 — — US disclosed
US-11666656-B2 Polymeric conjugates and uses thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-06-06 — — US disclosed
WO-2023280227-A2 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2023-01-12 — — WO disclosed
US-20070111926-A1 Conjugation of peptides NOVO NORDISK A/S (DK) 2007-05-17 — — US disclosed
CN-1863920-A Conjugation of peptides NOVO NORDISK AS (DK) 2006-11-15 — — CN disclosed
WO-2006084888-A2 C-TERMINALLY PEGYLATED GROWTH HORMONES NOVO NORDISK A/S (DK) 2006-08-17 — — WO disclosed
EP-1673464-A2 CONJUGATION OF PEPTIDES NOVO NORDISK A/S (DK) 2006-06-28 — — EP disclosed
WO-2005035553-A2 CONJUGATION OF PEPTIDES NOVO NORDISK A/S (DK) 2005-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11666656-B2 Polymeric conjugates and uses thereof CD44, DCLRE1A, CD74 KMT2A 1781/4885BLM 2687/4885ALOX15 4151/4885
US-20230277677-A1 POLYMERIC CONJUGATES AND USES THEREOF CD44, DCLRE1A, CD74 KMT2A 1781/4885BLM 2687/4885ALOX15 4151/4885
US-20090105134-A1 C-Terminally Pegylated Growth Hormones GHRHR, GHITM, HDGF KMT2A 3669/4885BLM 3645/4885ALOX15 4137/4885
US-11813334-B2 Polyethylene glycol conjugate drug, and preparation method therefor and use thereof FAR1, SLC10A1, THEM6 KMT2A 3322/4885BLM 3546/4885ALOX15 693/4885
US-20070111926-A1 Conjugation of peptides DNPEP, ENPEP, ANPEP KMT2A 2475/4885BLM 3002/4885ALOX15 2987/4885
US-20090253166-A1 Conjugation of Peptides DNPEP, ENPEP, ANPEP KMT2A 2475/4885BLM 3002/4885ALOX15 2987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.