SCHEMBL196988

SCHEMBL196988

CC(O)c1cccc(CCN)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 9/20 0.53
DRD2 P14416 3/20 0.53
DRD1 P21728 3/20 0.53
NOS1 P29475 1/20 0.49
KDM4E B2RXH2 2/20 0.46
ADRA2A P08913 2/20 0.46
MAPT P10636 2/20 0.46
DRD4 P21917 2/20 0.46
DRD5 P21918 2/20 0.46
SLC6A2 P23975 2/20 0.46
MAPK1 P28482 2/20 0.46
DRD3 P35462 2/20 0.46
RECQL P46063 2/20 0.46
SLC6A3 Q01959 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.46
ADRB2 P07550 1/20 0.46
HTR1A P08908 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841734 0.85 TAAR1 (0.57) TAAR1DRD2DRD1NOS1KDM4E
SCHEMBL29607349 0.85 ENPP2 (0.50) NOS1KDM4EALDH1A1ADRA1DLMNA
SCHEMBL27986627 0.85 ENPP2 (0.50) NOS1KDM4EALDH1A1ADRA1DLMNA
SCHEMBL8988941 0.85 ENPP2 (0.50) NOS1KDM4EALDH1A1ADRA1DLMNA
SCHEMBL26672647 0.83 TDP1 (0.45) TAAR1NOS1KDM4EMAPTTDP1
SCHEMBL10338275 0.83 TAAR1 (0.55) TAAR1DRD2DRD1NOS1SLC6A2
SCHEMBL28037741 0.83 TDP1 (0.45) TAAR1NOS1KDM4EMAPTTDP1
Hydrochloric Acid SCHEMBL14157281 0.83 TAAR1 (0.55) TAAR1DRD2DRD1NOS1KDM4E
SCHEMBL3029503 0.83 KDM4E (0.45) TAAR1DRD2DRD1NOS1KDM4E
SCHEMBL27939210 0.82 NOS1 (0.41) NOS1KDM4EMAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2895517-B1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECH AG (CH) 2020-12-16 EP claimed
US-20150259465-A1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECHNOLOGY AG (CH) 2015-09-17 US claimed
EP-2895517-A1 TWO-COMPONENT POLYURETHANE COMPOSITION Sika Technology AG (CH) 2015-07-22 EP claimed
WO-2014040922-A1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECHNOLOGY AG (CH) 2014-03-20 WO claimed
EP-2706073-A1 Two-component polyurethane composition Sika Technology AG (CH) 2014-03-12 EP claimed
US-8455100-B2 Aldimines comprising hydroxyl groups, and compositions containing aldimine SIKA TECHNOLOGY AG (CH) 2013-06-04 US claimed
US-8389772-B2 Aldehydes containing hydroxl groups SIKA TECHNOLOGY AG (CH) 2013-03-05 US claimed
US-8324340-B2 Polyurethane composition with good initial strength SIKA TECHNOLOGY AG (CH) 2012-12-04 US claimed
US-8252859-B2 Aldimines and compositions comprising aldimine SIKA TECHNOLOGY AG (CH) 2012-08-28 US claimed
US-20120107616-A1 Laminates Joined by Polyurethane Hot-Melt Adhesive and Process for Bonding Plasticizer-Containing Plastics SIKA TECHNOLOGY AG (CH) 2012-05-03 US claimed
EP-2030965-A1 Aldehydes containing hydroxyl groups Sika Technology AG (CH) 2009-03-04 EP claimed
EP-2030967-A1 Aldimines containing hydroxyl groups and compositions containing aldimine Sika Technology AG (CH) 2009-03-04 EP claimed
WO-2009010522-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE SIKA TECHNOLOGY AG (CH) 2009-01-22 WO claimed
EP-2017260-A1 Aldimines and compounds containing aldimine Sika Technology AG (CH) 2009-01-21 EP claimed
US-20080280145-A1 moisture-reactive hot-melt adhesive which comprises at least one aldimine and at least one polyurethane polymer ( polyesterurethane copolymer, polyetherurethane copolymer)which contains isocyanate groups and is solid at room temperature; bonded assembly is notable for improved adhesive SIKA TECHNOLOGY AG (CH) 2008-11-13 US claimed
EP-1990387-A1 Composite layer body joined with polyurethane holt melt glue and method for gluing plastics containing dilutents Sika Technology AG (CH) 2008-11-12 EP claimed
WO-2008116928-A1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN SIKA TECHNOLOGY AG (CH) 2008-10-02 WO claimed
EP-1975190-A1 Aldimines with reactive groups containing active hydrogen Sika Technology AG (CH) 2008-10-01 EP claimed
WO-2008052999-A1 POLYURETHANE COMPOSITION WITH GOOD INITIAL STRENGTH SIKA TECHNOLOGY AG (CH) 2008-05-08 WO claimed
EP-1918314-A1 Polyurethane composition with high green strength Sika Technology AG (CH) 2008-05-07 EP claimed