Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 6/20 | 0.46 |
| ▸ | NOS2 | P35228 | 6/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 4/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607349 | 1.00 | ENPP2 (0.50) | ENPP2NOS1NOS2PNMTNOS3 | |
| SCHEMBL27986627 | 1.00 | ENPP2 (0.50) | ENPP2NOS1NOS2PNMTNOS3 | |
| SCHEMBL27939210 | 0.88 | NOS1 (0.41) | ENPP2NOS1NOS2PNMTNOS3 | |
| SCHEMBL196988 | 0.85 | TAAR1 (0.53) | NOS1LOXL2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12831490 | 0.83 | PNMT (0.48) | ENPP2NOS1NOS2PNMTNOS3 | |
| SCHEMBL21700186 | 0.83 | ENPP2 (0.54) | ENPP2NOS1NOS2PNMTNOS3 | |
| SCHEMBL84035 | 0.83 | PNMT (0.48) | ENPP2NOS1NOS2PNMTNOS3 | |
| SCHEMBL6533707 | 0.83 | ENPP2 (0.54) | ENPP2NOS1NOS2PNMTNOS3 | |
| SCHEMBL24792245 | 0.82 | ENPP2 (0.52) | ENPP2NOS1NOS2PNMTNOS3 | |
| SCHEMBL3919972 | 0.82 | PTGS2 (0.46) | CYP3A4MEN1KMT2AUGT2B7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104262093-A | R-1-(3-methylphenyl)ethanol and synthesis of ester thereof | WANG TONGJUN | 2015-01-07 | — | — | CN | claimed |
| CN-106478325-B | A method of synthesis alpha-alkyl ketone | 南京理工大学 | 2019-06-25 | — | — | CN | disclosed |
| CN-109134267-A | A kind of synthetic method of aromatic amine compounds | 北京大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-104988165-B | Esterase est4, esterase EST4, recombinant plasmid and engineering strain and its application | 华东理工大学 | 2018-03-23 | — | — | CN | disclosed |
| CN-106478325-A | A kind of method of synthesis alpha-alkyl ketone | 南京理工大学 | 2017-03-08 | — | — | CN | disclosed |
| CN-104988165-A | Esterase est4, esterase EST4, recombinant plasmid and gene engineering strain and applications thereof | UNIV EAST CHINA SCIENCE & TECH | 2015-10-21 | — | — | CN | disclosed |
| CN-104262093-A | R-1-(3-methylphenyl)ethanol and synthesis of ester thereof | WANG TONGJUN | 2015-01-07 | — | — | CN | disclosed |
| CN-101974602-A | Method for preparing (R)-type chiral aryl secondary alcohol | UNIV GUANGXI | 2011-02-16 | — | — | CN | disclosed |
| CN-101277913-A | Method for fractionating stereoisomeric compounds | BASF AG (DE) | 2008-10-01 | — | — | CN | disclosed |
| CN-101125833-A | Optically active bisoxazoline compounds, process for production of the same and use thereof | SUMITOMO CHEMICAL CO (JP) | 2008-02-20 | — | — | CN | disclosed |
| CN-1771236-A | Optically active bisoxazoline compound, process for producing the same, and use thereof | SUMITOMO CHEMICAL CO (JP) | 2006-05-10 | — | — | CN | disclosed |
| CN-1231456-C | Process for preparing optically active cyclopropyl carboxylic acid derivative | SUMITOMO CHEMICAL CO (JP) | 2005-12-14 | — | — | CN | disclosed |
| CN-1480448-A | Process for preparing optically active cyclopropyl carboxylic acid derivative | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-03-10 | — | — | CN | disclosed |
| CN-1134422-C | Optically active bisoxazoline compounds, process for their preparation and their use | ������������ʽ���� | 2004-01-14 | — | — | CN | disclosed |
| CN-1266904-A | Process for preparing stereoisomer carboxylate | BASF AG (DE) | 2000-09-20 | — | — | CN | disclosed |
| CN-1210858-A | Optically active bisoxazoline compounds, process for their preparation and their use | SUMITOMO CHEMICAL CO (JP) | 1999-03-17 | — | — | CN | disclosed |
| EP-0719262-A1 | 3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE-3-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND DRUGS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007899-A1 | 3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE-3-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-03-23 | — | — | WO | disclosed |
| CN-1017619-B | SUBSTITUTED AMINE DERIVATIVES PRODN. AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-07-29 | — | — | CN | disclosed |
| CN-88100804-A | Substituted amine derivatives, their preparation and use | — | 1988-08-24 | — | — | CN | disclosed |