SCHEMBL19700417

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19776798	0.76	TSHR (0.45)	TSHRMEN1KMT2AALDH1A1SLC6A2
	SCHEMBL3251403	0.76	TSHR (0.45)	TSHRMEN1KMT2AALDH1A1SLC6A2
	SCHEMBL2046868	0.76	MEN1 (0.49)	TSHRMEN1KMT2AALDH1A1SLC6A2
	Hydrochloric Acid SCHEMBL9876959	0.74	TSHR (0.43)	TSHRMEN1KMT2AALDH1A1SLC6A2
	Methylhydrazine SCHEMBL28151890	0.69	MEN1 (0.46)	TSHRMEN1KMT2AALDH1A1SLC6A2
	SCHEMBL3635237	0.68	TSHR (0.54)	TSHRMEN1KMT2AALDH1A1SLC6A2
	SCHEMBL608453	0.68	TSHR (0.54)	TSHRMEN1KMT2AALDH1A1SLC6A2
	SCHEMBL6254423	0.67	MAOB (0.46)	MEN1KMT2AALDH1A1SLC6A2SLC6A4
	Hydrochloric Acid SCHEMBL27658035	0.66	TSHR (0.52)	TSHRMEN1KMT2AALDH1A1SLC6A2
	SCHEMBL530326	0.66	ADRA2B (0.67)	TSHRMEN1KMT2AALDH1A1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.