Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP4B1 | P13584 | 3/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.42 |
| ▸ | CYP2A7 | P20853 | 3/20 | 0.42 |
| ▸ | CYP3A7 | P24462 | 3/20 | 0.42 |
| ▸ | CYP2F1 | P24903 | 3/20 | 0.42 |
| ▸ | CYP2C18 | P33260 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | CYP4F8 | P98187 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27394748 | 0.89 | CYP1B1 (0.53) | CYP1B1CYP1A1ALDH1A3STIM1ORAI1 | |
| SCHEMBL19454746 | 0.83 | CHRNB2 (0.53) | CYP1B1ALDH1A3STIM1ORAI1ALDH1A1 | |
| SCHEMBL21955600 | 0.82 | KDM4E (0.41) | CYP1B1 | |
| SCHEMBL12427200 | 0.81 | MEN1 (0.55) | CYP1B1ALDH1A3NPC1RAB9AMEN1 | |
| SCHEMBL19700923 | 0.77 | CYP1B1 (0.59) | CYP1B1CYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL22308430 | 0.76 | CYP1B1 (0.58) | CYP1B1CYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL19707871 | 0.74 | HDAC3 (0.43) | CYP1B1ALDH1A3STIM1ORAI1ALDH1A1 | |
| SCHEMBL3589343 | 0.73 | LGALS3 (0.37) | CYP1B1 | |
| SCHEMBL17084697 | 0.72 | KDM4E (0.46) | — | |
| SCHEMBL31510906 | 0.72 | KMT2A (0.52) | CYP1B1CYP1A1CYP1A2CYP2E1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210054017-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | IONIS PHARMACEUTICALS INC (US) | 2021-02-25 | — | — | US | disclosed |
| US-20170355727-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | IONIS PHARMACEUTICALS, INC. (US) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210054017-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | GNE, FUT6, GALNT13 | CYP1B1 3252/4885CYP1A1 3133/4885CYP1A2 4116/4885 |
| US-20170355727-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | GNE, GALNT1, GALNT6 | CYP1B1 4055/4885CYP1A1 3926/4885CYP1A2 4660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.