SCHEMBL197017

SCHEMBL197017

c1ccc(COc2ccc(-c3ccc(OCc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.72
CYP1A2 P05177 1/20 0.72
PTGS1 P23219 1/20 0.72
SLC6A2 P23975 1/20 0.72
CYP2C19 P33261 1/20 0.72
PTGS2 P35354 1/20 0.72
SLC6A3 Q01959 1/20 0.72
HIF1A Q16665 1/20 0.72
HDAC6 Q9UBN7 1/20 0.72
MAOB P27338 4/20 0.69
GAA P10253 2/20 0.69
RAB9A P51151 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
MAPT P10636 1/20 0.69
MAOA P21397 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
GSTP1 P09211 2/20 0.69
BCHE P06276 1/20 0.64
NR4A1 P22736 1/20 0.62
NR4A2 P43354 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23483029 0.98 LMNA (0.69) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL1096817 0.98 LMNA (0.69) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6059308 0.94 LMNA (0.64) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL27367676 0.93 LMNA (0.82) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL339813 0.93 LMNA (0.82) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL254671 0.92 LMNA (0.88) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL9617467 0.92 LMNA (0.62) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL1703352 0.91 APP (0.69) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6059234 0.90 LMNA (0.85) LMNACYP1A2PTGS1SLC6A2CYP2C19
Bicarbonate SCHEMBL9638235 0.90 FFAR1 (0.71) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60079996-A None JP disclosed
US-9399712-B2 Vinylbenzyl-etherified-DOPO compound resin composition and preparation and application thereof ELITE ELECTRONIC MATERIAL (ZHONG SHAN) CO., LTD. (CN) 2016-07-26 US disclosed
US-9123689-B2 Epoxy resin composition, method for producing same, and semiconductor device using same TORAY INDUSTRIES, INC. (JP) 2015-09-01 US disclosed
US-20150166788-A1 VINYLBENZYL-ETHERIFIED-DOPO COMPOUND RESIN COMPOSITION AND PREPARATION AND APPLICATION THEREOF ELITE ELECTRONIC MATERIAL (ZHONG SHAN) CO., LTD. (CN) 2015-06-18 US disclosed
EP-2390241-B1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-10-01 EP disclosed
US-8598349-B2 Method for manufacturing conjugated aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-03 US disclosed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
US-8088883-B2 Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-03 US disclosed
EP-2390241-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-11-30 EP disclosed
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2011-11-10 US disclosed
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED 2011-02-24 US disclosed
US-20100292481-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2010-11-18 US disclosed
EP-2233459-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-09-29 EP disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed
US-5196606-A Aromatic tertiary amines, enamines, deoxybenzoins and benzils HAY ALLAN S (CA) 1993-03-23 US disclosed
US-5117062-A Aromatic tertiary amines, enamines, deoxybenzoins and benzils HAY ALLAN S (CA) 1992-05-26 US disclosed
US-5011998-A Aromatic tertiary amines, enamines, deoxybenzoins and benzils HAY ALLAN S (CA) 1991-04-30 US disclosed
JP-S6079996-A THERMAL RECORDING PAPER UENO SEIYAKU OYO KENKYUSHO:KK 1985-05-07 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND C9, H1-10, CYP1A1 LMNA 1269/4885CYP1A2 108/4885PTGS1 3627/4885
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP1M1 LMNA 2664/4885CYP1A2 191/4885PTGS1 3194/4885
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 LMNA 3345/4885CYP1A2 228/4885PTGS1 2847/4885
US-20100292481-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND TYR, PAH, AHR LMNA 2021/4885CYP1A2 856/4885PTGS1 4029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.