Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196649 | 0.88 | MAPT (0.43) | FAAHALDH1A1KDM4EHCAR2KEAP1 | |
| SCHEMBL196650 | 0.88 | MAPT (0.43) | FAAHALDH1A1KDM4EHCAR2KEAP1 | |
| SCHEMBL29393125 | 0.85 | ALDH1A1 (0.39) | FAAHALDH1A1KDM4EHCAR2KEAP1 | |
| SCHEMBL2615390 | 0.85 | HCAR2 (0.52) | FAAHALDH1A1KDM4EHCAR2KEAP1 | |
| SCHEMBL2609694 | 0.84 | FAAH (0.54) | FAAHALDH1A1HCAR2KEAP1NFE2L2 | |
| SCHEMBL17777272 | 0.81 | HCAR2 (0.43) | ALDH1A1KDM4EHCAR2KEAP1NFE2L2 | |
| SCHEMBL19701742 | 0.80 | HCAR2 (0.46) | ALDH1A1KDM4EHCAR2KEAP1NFE2L2 | |
| SCHEMBL2609695 | 0.79 | CYP1A2 (0.52) | ALDH1A1KDM4EHCAR2KEAP1NFE2L2 | |
| SCHEMBL18292232 | 0.78 | FAAH (0.59) | FAAHALDH1A1HCAR2MAPTMEN1 | |
| SCHEMBL24098107 | 0.78 | TSHR (0.50) | FAAHKDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180000770-A1 | Methods of Treating Multiple Sclerosis | BIOGEN MA INC (US) | 2018-01-04 | — | — | US | disclosed |
| US-20170368013-A1 | Methods of Treating Multiple Sclerosis | BIOGEN MA INC. | 2017-12-28 | — | — | US | disclosed |
| US-20170354630-A1 | Methods of Treating Multiple Sclerosis | BIOGEN MA INC. | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170368013-A1 | Methods of Treating Multiple Sclerosis | FAH, FH, PML | FAAH 81/4885ALDH1A1 3424/4885KDM4E 1510/4885 |
| US-20180000770-A1 | Methods of Treating Multiple Sclerosis | FAH, FH, PML | FAAH 81/4885ALDH1A1 3424/4885KDM4E 1510/4885 |
| US-20170354630-A1 | Methods of Treating Multiple Sclerosis | FAH, FH, PML | FAAH 81/4885ALDH1A1 3424/4885KDM4E 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.