Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839253 | 0.85 | APP (0.63) | APPFFAR1MAPTHAO1PPARG | |
| SCHEMBL6727043 | 0.83 | LTA4H (0.60) | APPFFAR1MAPTHAO1CHRNB2 | |
| SCHEMBL14380094 | 0.83 | LTA4H (0.60) | APPFFAR1MAPTHAO1CHRNB2 | |
| SCHEMBL13283919 | 0.80 | LTA4H (0.68) | APPFFAR1MAPTHAO1 | |
| SCHEMBL6287635 | 0.80 | LTA4H (0.63) | APPFFAR1MAPTCA1CA2 | |
| SCHEMBL5414558 | 0.79 | APP (0.55) | APPFFAR1MAPTHAO1CHRNB2 | |
| SCHEMBL5406443 | 0.79 | APP (0.55) | APPFFAR1MAPTHAO1PPARG | |
| SCHEMBL2114741 | 0.79 | APP (0.92) | APPFFAR1MAPTNPC1FFAR4 | |
| SCHEMBL5552160 | 0.76 | APP (0.65) | APPFFAR1MAPTCHRNB2CHRNB4 | |
| SCHEMBL88339 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355907-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICALLY ANISOTROPIC BODY, PHASE DIFFERENCE FILM, ANTIREFLECTION FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT PRODUCED USING COMPOSITION | DIC CORPORATION (JP) | 2017-12-14 | — | — | US | disclosed |