SCHEMBL6287635

SCHEMBL6287635

C(#Cc1ccc(Oc2ccccc2)cc1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.63
TSHR P16473 1/20 0.63
APP P05067 1/20 0.55
GRM5 P41594 1/20 0.54
NR1H2 P55055 1/20 0.54
BAX Q07812 1/20 0.54
MAOA P21397 1/20 0.54
FFAR1 O14842 3/20 0.51
PLA2G2A P14555 1/20 0.50
ACACB O00763 1/20 0.49
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14380094 0.97 LTA4H (0.60) LTA4HTSHRAPPGRM5NR1H2
SCHEMBL6727043 0.97 LTA4H (0.60) LTA4HTSHRAPPGRM5NR1H2
SCHEMBL3839253 0.95 APP (0.63) LTA4HTSHRAPPGRM5NR1H2
SCHEMBL5414558 0.88 APP (0.55) LTA4HTSHRAPPGRM5NR1H2
SCHEMBL5406443 0.88 APP (0.55) LTA4HTSHRAPPGRM5NR1H2
SCHEMBL27673051 0.86 LTA4H (0.52) LTA4HTSHRGRM5NR1H2BAX
SCHEMBL17348045 0.86 CYP1A1 (0.59) LTA4HTSHRGRM5NR1H2BAX
SCHEMBL13283919 0.84 LTA4H (0.68) LTA4HAPPNR1H2BAXFFAR1
SCHEMBL3085615 0.84 FFAR1 (0.52) LTA4HTSHRAPPGRM5NR1H2
SCHEMBL14380097 0.84 GRM5 (0.51) LTA4HTSHRAPPGRM5NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6979737-B1 Quinoxaline-containing AB2 monomer for hyperbranched aromatic poly(ether-ketones) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2005-12-27 US disclosed
US-5374701-A Crosslinkable polymers of high strength free of structural defects HAY ALLAN S (CA) 1994-12-20 US disclosed
US-5233046-A DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION HAY ALLAN S (CA) 1993-08-03 US disclosed
WO-1993009079-A1 DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION HAY ALAN S (CA) 1993-05-13 WO disclosed
US-4131748-A P-Terphenylene-dicarboxylic acids and their synthesis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1978-12-26 US disclosed
US-4108835-A Phenylated aromatic heterocyclic polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1978-08-22 US disclosed