Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3588245 | 0.69 | ATM (0.56) | RAB9ANPC1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL19707595 | 0.68 | MEN1 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL19707659 | 0.68 | NPY5R (0.56) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19707210 | 0.68 | FPR2 (0.46) | RAB9ANPC1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14413756 | 0.67 | RAB9A (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19707706 | 0.67 | MEN1 (0.45) | RAB9ANPC1ALDH1A1KMT2AKCNH2 | |
| SCHEMBL19708112 | 0.66 | MEN1 (0.47) | RAB9ANPC1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL31637520 | 0.66 | RAB9A (0.96) | RAB9ANPC1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL19707295 | 0.65 | MEN1 (0.46) | RAB9ANPC1ALDH1A1TDP1KMT2A | |
| SCHEMBL22777886 | 0.64 | KDM4E (0.94) | RAB9ANPC1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |