Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707659 | 0.79 | NPY5R (0.56) | MEN1KMT2AS1PR3FPR2ALDH1A1 | |
| SCHEMBL19707210 | 0.74 | FPR2 (0.46) | MEN1KMT2AFPR2ALDH1A1RAB9A | |
| SCHEMBL19707706 | 0.73 | MEN1 (0.45) | MEN1KMT2AS1PR3FPR2ALDH1A1 | |
| SCHEMBL19707831 | 0.73 | NPY5R (0.47) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL19708112 | 0.70 | MEN1 (0.47) | MEN1KMT2AFPR2ALDH1A1RAB9A | |
| SCHEMBL19707292 | 0.68 | KMT2A (0.44) | MEN1KMT2AS1PR3FPR2ALDH1A1 | |
| SCHEMBL19708072 | 0.68 | MEN1 (0.66) | MEN1KMT2ARAB9ANPC1TDP1 | |
| SCHEMBL19707595 | 0.68 | MEN1 (0.50) | MEN1KMT2AFPR2ALDH1A1RAB9A | |
| SCHEMBL7609572 | 0.67 | RAB9A (0.53) | MEN1KMT2AFPR2ALDH1A1RAB9A | |
| SCHEMBL19707634 | 0.65 | RAB9A (0.50) | MEN1KMT2AFPR2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |