Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12550520 | 0.82 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL19707921 | 0.80 | LSS (0.36) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11925050 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2LMNAALOX5TP53 | |
| SCHEMBL14672264 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2LMNAALOX5TP53 | |
| SCHEMBL7980047 | 0.78 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAALOX5TP53 | |
| SCHEMBL10266900 | 0.76 | MLYCD (0.56) | ALDH1A1L3MBTL1LMNAALOX5MAPT | |
| SCHEMBL28448449 | 0.75 | MEN1 (0.42) | ALDH1A1SMN1; SMN2LMNAALOX5TP53 | |
| SCHEMBL2095642 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL969001 | 0.72 | SMN1; SMN2 (0.52) | ALDH1A1L3MBTL1SMN1; SMN2LMNATP53 | |
| SCHEMBL2095645 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |