Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362086 | 0.76 | CES2 (0.44) | MAPK1TAAR1HRH1SLC6A3TSHR | |
| SCHEMBL28495047 | 0.75 | HCAR2 (0.39) | TAAR1HRH1CACNA1FCHRM2CHRM1 | |
| SCHEMBL11145431 | 0.69 | MAPK1 (0.44) | MAPK1TAAR1SLC6A3TRPA1 | |
| SCHEMBL3126772 | 0.69 | TAAR1 (0.61) | TAAR1HRH1CHRM2ADRA1ASLC6A3 | |
| SCHEMBL3925766 | 0.69 | CES2 (0.38) | TAAR1TSHRTRPA1CES2CES1 | |
| SCHEMBL6478846 | 0.68 | SCN1A (0.36) | MAPK1TAAR1HRH1CHRM2CHRM1 | |
| SCHEMBL2736711 | 0.68 | TAAR1 (0.58) | TAAR1HRH1AOC3TSHRLMNA | |
| SCHEMBL6583604 | 0.68 | TAAR1 (0.58) | TAAR1HRH1AOC3TSHRLMNA | |
| SCHEMBL2220602 | 0.68 | KMT2A (0.41) | TAAR1HRH1TSHRLMNAALDH1A1 | |
| SCHEMBL8160126 | 0.68 | TSHR (0.43) | TAAR1HRH1TSHRLMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509956-A1 | CYSTEINE PROTEASE INHIBITORS | Medivir UK Ltd (GB) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070539-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR UK LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |
| WO-1994019023-A1 | CYCLOBUTYL ANTISENSE OLIGONUCLEOTIDES, METHODS OF MAKING AND USE THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 1994-09-01 | — | — | WO | disclosed |