Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11777006 | 0.97 | KMT2A (0.40) | KMT2ATAAR1CES2CES1TRPA1 | |
| SCHEMBL6930765 | 0.95 | KMT2A (0.39) | KMT2ATAAR1CES2CES1TRPA1 | |
| SCHEMBL30692060 | 0.87 | CYP3A4 (0.48) | KMT2ATAAR1CES2CES1TRPA1 | |
| SCHEMBL11513291 | 0.78 | CES2 (0.44) | TAAR1CES2CES1TRPA1DPP4 | |
| SCHEMBL8362086 | 0.78 | CES2 (0.44) | TAAR1CES2CES1TRPA1DPP4 | |
| SCHEMBL28546195 | 0.75 | KMT2A (0.43) | KMT2ATAAR1CES2CES1TRPA1 | |
| SCHEMBL1964140 | 0.75 | THRB (0.46) | KMT2ATAAR1CES2CES1TRPA1 | |
| SCHEMBL83160 | 0.74 | KMT2A (0.46) | KMT2ACES2CES1EPHX1THRB | |
| SCHEMBL8923611 | 0.74 | CES2 (0.41) | KMT2ATAAR1CES2CES1TRPA1 | |
| SCHEMBL7699358 | 0.73 | UGT2B7 (0.52) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087163-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2021-03-25 | — | — | US | claimed |
| EP-2544535-B1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIV (US) | 2017-04-19 | — | — | EP | claimed |
| US-20160237058-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2016-08-18 | — | — | US | claimed |
| EP-3049072-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | William Marsh Rice University (US) | 2016-08-03 | — | — | EP | claimed |
| WO-2015048268-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2015-04-02 | — | — | WO | claimed |
| US-20130345196-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2013-12-26 | — | — | US | claimed |
| US-20130345235-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-12-26 | — | — | US | claimed |
| EP-2544535-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | North Carolina Central University (US) | 2013-01-16 | — | — | EP | claimed |
| WO-2011112858-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-09-15 | — | — | WO | claimed |
| WO-2011084503-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-07-14 | — | — | WO | claimed |
| EP-0831769-A2 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | KARO BIO AB (SE) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040048-A2 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | KARO BIO AB (SE) | 1996-12-19 | — | — | WO | claimed |
| CN-116813550-B | Indazole derivative, preparation method, pharmaceutical composition and application thereof | Shanghai Pharmaceutical Industry Research Institute Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-12384860-B2 | Hybrid supported metallocene catalyst and process for preparing polyethylene copolymer using the same | LG CHEM, LTD. (KR) | 2025-08-12 | — | — | US | disclosed |
| US-20240352022-A1 | GROUP OF IMB-C5 SERIES COMPOUNDS HAVING ANTI-CORONAVIRUS ACTIVITY AND APPLICATION THEREOF | INSTITUTE OF MEDICINAL BIOTECHNOLOGY CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2024-10-24 | — | — | US | disclosed |
| CN-115785080-B | Uracil parent nucleus compound and preparation method and application thereof | 陕西盘龙药业集团股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| EP-0311694-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | RIKAGAKU KENKYUSHO (JP) | 1989-04-19 | — | — | EP | disclosed |
| EP-0303087-A2 | Polymeric dihydroxy compounds and use thereof as stabilizers for polymers | BAYER AG (DE) | 1989-02-15 | — | — | EP | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |
| EP-0040408-A1 | Beta-lactam compounds and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130345235-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | CES2, TOP1, GUSB | KMT2A 2947/4885TAAR1 3652/4885CES2 1/4885 |
| US-20160237058-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, PNP | KMT2A 3816/4885TAAR1 3261/4885CES2 7/4885 |
| US-20130345196-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, TOP2B | KMT2A 3685/4885TAAR1 3007/4885CES2 7/4885 |
| US-20240352022-A1 | GROUP OF IMB-C5 SERIES COMPOUNDS HAVING ANTI-CORONAVIRUS ACTIVITY AND APPLICATION THEREOF | ACE2, C5, ACE | KMT2A 4863/4885TAAR1 4821/4885CES2 2435/4885 |
| US-20210087163-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, PNP | KMT2A 3816/4885TAAR1 3261/4885CES2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.