Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3925766 | 0.85 | CES2 (0.38) | CES2CES1TRPA1CYP2D6DPP4 | |
| SCHEMBL28495047 | 0.83 | HCAR2 (0.39) | CES2CES1TRPA1CYP2D6TAAR1 | |
| SCHEMBL11513291 | 0.82 | CES2 (0.44) | CES2CES1TRPA1CYP2D6DPP4 | |
| SCHEMBL2220602 | 0.78 | KMT2A (0.41) | CES2CES1TRPA1DPP4F2 | |
| SCHEMBL8923611 | 0.78 | CES2 (0.41) | CES2CES1TRPA1CYP2D6DPP4 | |
| SCHEMBL1970776 | 0.76 | MAPK1 (0.44) | CES2CES1TRPA1TSHRTAAR1 | |
| SCHEMBL3485914 | 0.76 | SLC6A4 (0.41) | CES2CES1TRPA1DPP4F2 | |
| Hydrochloric Acid SCHEMBL11777006 | 0.76 | KMT2A (0.40) | CES2CES1TRPA1DPP4F2 | |
| SCHEMBL6930765 | 0.74 | KMT2A (0.39) | CES2CES1TRPA1CYP2D6DPP4 | |
| SCHEMBL7563457 | 0.72 | L3MBTL1 (0.42) | CES2CES1TRPA1CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003822-A | SG3C bromobenzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2023-11-07 | — | — | CN | claimed |
| CN-117003815-A | SG2C bromobenzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2023-11-07 | — | — | CN | claimed |
| CN-111943876-B | N2S2 bromo-benzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2022-04-19 | — | — | CN | claimed |
| CN-109195960-B | Bromo-benzyl ether derivative, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2021-05-04 | — | — | CN | claimed |
| CN-111943876-A | N2S2 bromo-benzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2020-11-17 | — | — | CN | claimed |
| CN-108069956-A | 1- azabicyclos [2,2,2] octyl- 4- base phenyl ketone compounds and its preparation method and application | 扬州奥锐特药业有限公司 | 2018-05-25 | — | — | CN | claimed |
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-103420949-B | A kind of separation method of epoxychloropropane | SINOPEC CORP. (CN) | 2016-05-25 | — | — | CN | claimed |
| CN-104530417-A | Multifunctional H-type polyethylene glycol derivative and preparation method thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104109235-A | Mono-functionalized polyethylene glycol with nitrogen atom branched center and its preparation method and biologically-relevant matter | XIAMEN SINOPEG BIOTECH CO LTD | 2014-10-22 | — | — | CN | claimed |
| CN-100355772-C | Steroid compound with 5-alpha reductase active and preparation process thereof | UNIV TIANJIN (CN) | 2007-12-19 | — | — | CN | claimed |
| CN-1793164-A | Steroid compound with 5-alpha reductase active and preparation process thereof | UNIV TIANJIN (CN) | 2006-06-28 | — | — | CN | claimed |
| CN-117003815-A | SG2C bromobenzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2023-11-07 | — | — | CN | disclosed |
| CN-117003815-A | SG2C bromobenzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2023-11-07 | — | — | CN | disclosed |
| CN-117003815-A | SG2C bromobenzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2023-11-07 | — | — | CN | disclosed |
| CN-1793164-A | Steroid compound with 5-alpha reductase active and preparation process thereof | UNIV TIANJIN (CN) | 2006-06-28 | — | — | CN | disclosed |
| CN-1738713-A | Laminated structure excellent in fuel permeation preventing performance | UBE INDUSTRIES (JP) | 2006-02-22 | — | — | CN | disclosed |
| WO-1999041216-A1 | SUPPORTS FOR SOLID STATE CHEMICAL REACTIONS AND METHOD OF USE THEREOF | CHEMBRIDGE CORPORATION (US) | 1999-08-19 | — | — | WO | disclosed |