Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 4/20 | 0.56 |
| ▸ | RHOA | P61586 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707481 | 0.86 | MAPT (0.54) | HTTALDH1A1P2RX1CES2PTGS1 | |
| SCHEMBL27676491 | 0.83 | RHOC (0.53) | RHOCRHOAALDH1A1HPGDP2RX1 | |
| SCHEMBL19707256 | 0.83 | ERCC5 (0.55) | ALDH1A1HPGDKCNQ3KCNQ2KCNE1 | |
| SCHEMBL19707219 | 0.82 | NPC1 (0.49) | HTTALDH1A1HPGDCNR1CES2 | |
| SCHEMBL19707493 | 0.81 | CNR1 (0.53) | ALDH1A1HPGDP2RX1CNR1MGLL | |
| SCHEMBL23014506 | 0.80 | CCR2 (0.63) | RHOCRHOAALDH1A1CCR2TP53 | |
| SCHEMBL27816991 | 0.80 | CES2 (0.59) | ALDH1A1P2RX1CES2KCNQ3KCNQ2 | |
| SCHEMBL28057626 | 0.80 | CES2 (0.59) | HTTALDH1A1P2RX1CES2PTGS1 | |
| SCHEMBL11503483 | 0.79 | DDR1 (0.59) | RHOCRHOAHTTALDH1A1HPGD | |
| SCHEMBL5131380 | 0.79 | RHOC (0.80) | RHOCRHOAHTTP2RX1KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190134005-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARM INC (US) | 2019-05-09 | — | — | US | disclosed |
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190134005-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | UGCG, MAN2B1, GBA1 | RHOC 3868/4885RHOA 3861/4885HTT 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.