⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20936293 | 0.93 | — | — | |
| SCHEMBL13959889 | 0.70 | — | — | |
| SCHEMBL7030729 | 0.68 | — | — | |
| SCHEMBL122141 | 0.68 | BRD4 (0.41) | — | |
| SCHEMBL13959902 | 0.68 | MEN1 (0.40) | — | |
| SCHEMBL21627160 | 0.67 | KDM4E (0.31) | — | |
| SCHEMBL22268216 | 0.67 | — | — | |
| SCHEMBL22268222 | 0.67 | — | — | |
| SCHEMBL12598827 | 0.67 | SIGMAR1 (0.30) | — | |
| SCHEMBL1625501 | 0.67 | MITF (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200317678-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARM INC (US) | 2020-10-08 | — | — | US | disclosed |
| US-10189846-B2 | Hepatitis B antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170355701-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2017-12-14 | — | — | US | disclosed |