Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 7/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5091347 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5093099 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL1517962 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL422617 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL3216257 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL1023018 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5086746 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL3112034 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL9574841 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5086682 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3065 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120682125-B | 1-Hydroxy-1-sodium sulfonate structural compound based on cinnamaldehyde derivative, and preparation method and application thereof | 中国农业大学 | 2026-05-15 | — | — | CN | claimed |
| EP-4713317-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | Adama Agan Ltd. (IL) | 2026-03-25 | — | — | EP | claimed |
| EP-4638452-A1 | PROCESS FOR THE PREPARATION OF 7-(4-CHLOROBENZYL)-1-(3-HYDROXYPROPYL)-3-METHYL-8-(3-(TRIFLUOROMETHOXY)-PHENOXY)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | Boehringer Ingelheim International GmbH (DE) | 2025-10-29 | — | — | EP | claimed |
| US-12344784-B2 | Stabilized perovskite quantum dot material | QUANTUM ADVANCED SOLUTIONS LIMITED (GB) | 2025-07-01 | — | — | US | claimed |
| CN-111718716-B | Nanostructure with inorganic ligands for electroluminescent devices | 昭荣化学工业株式会社 | 2025-06-10 | — | — | CN | claimed |
| US-20250154401-A1 | REDUCED-POLYMER-LOADING, HIGH-TEMPERATURE FRACTURING FLUIDS AND METHODS AND SYSTEMS RELATED THERETO | SAUDI ARABIAN OIL COMPANY (SA) | 2025-05-15 | — | — | US | claimed |
| CN-119706808-A | Two-dimensional fluorine-doped carbon nano sheet and preparation and application thereof | 中国科学院大连化学物理研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-119666830-A | Visual array sensor constructed based on oxidation reaction of nano porphyrin and oxidant on different-level West lake Longjing at different production areas and application thereof | 中南民族大学 | 2025-03-21 | — | — | CN | claimed |
| US-12209218-B2 | Reduced-polymer-loading, high-temperature fracturing fluids and methods and systems related thereto | SAUDI ARABIAN OIL COMPANY (SA) | 2025-01-28 | — | — | US | claimed |
| CN-119264033-A | Synthesis method of oxygen-18 substituted Abediterol precursor | 中国科学技术大学 | 2025-01-07 | — | — | CN | claimed |
| US-4451679-A | RUTHENIUM COMPOUNDS, PHOSPHONIUM OR QUATERNARY AMMONIUM COMPOUNDS | TEXACO INC. (US) | 1984-05-29 | — | — | US | claimed |
| US-4451680-A | RUTHENIUM COMPOUND, BIDENTATE OR MULTIDENTATE PHOSPHINE, PHOSPHONIUM COMPOUND | TEXACO INC. (US) | 1984-05-29 | — | — | US | claimed |
| EP-0074272-A1 | Process for the preparation of hydroxybenzaldehydes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-03-16 | — | — | EP | claimed |
| EP-0004460-B1 | IMPROVED SYNTHESIS OF 1,4-DIAZA-2-CYCLOALKANONE AND SUBSTITUTED DERIVATIVES THEREOF | The B.F. GOODRICH Company (US) | 1983-03-09 | — | — | EP | claimed |
| US-4359429-A | Mercaptoacetonitrile synthesis | W. R. GRACE & CO. (US) | 1982-11-16 | — | — | US | claimed |
| US-4338290-A | HYDROGEN IODIDE ACID CATALYST | NATIONAL DISTILLERS & CHEMICAL CORP. (US) | 1982-07-06 | — | — | US | claimed |
| US-4200761-A | Process for preparing N-cyano-N'methyl-N\"-{2-[(4-methyl-5-imidazolyl)-methylthio]-ethyl} guanidine | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1980-04-29 | — | — | US | claimed |
| US-4191702-A | PHASE TRANSFER AGENT | ELF UNION (FR) | 1980-03-04 | — | — | US | claimed |
| US-4140516-A | Encapsulation process employing phase transfer catalysts | STAUFFER CHEMICAL COMPANY (US) | 1979-02-20 | — | — | US | claimed |
| US-4092306-A | Oxidation of hydrazones to the corresponding diazo compounds in the presence of a phase transfer and an oxidation catalyst which is iodine, an iodide or an iodonium salt | GLAXO LABORATORIES LIMITED (EN) | 1978-05-30 | — | — | US | claimed |