Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 7/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5091347 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5093099 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL197090 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL1517962 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL422617 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL3216257 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL1023018 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5086746 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL3112034 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5086682 | 1.00 | DNM1 (1.00) | DNM1TSHRTHRBBDKRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534380-A1 | Agent and method for enhancing chemiluminescence | KYOTO DAIICHI KAGAKU CO., LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |