SCHEMBL1970949

SCHEMBL1970949

COCCOC(C)N1C(=O)C=CC1=O

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
MGLL Q99685 6/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
FAAH O00519 2/20 0.31
GMNN O75496 1/20 0.31
THPO P40225 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
HSP90AA1 P07900 1/20 0.30
TLR9 Q9NR96 1/20 0.30
TP53 P04637 1/20 0.30
PKM P14618 1/20 0.30
HPGD P15428 1/20 0.30
XBP1 P17861 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28884160 0.79 SMN1; SMN2 (0.47) ALDH1A1MGLLLMNAMAPTNPSR1
SCHEMBL2607935 0.78 MGLL (0.39) ALDH1A1MGLLLMNAMAPTNPSR1
SCHEMBL2835666 0.74 MGLL (0.38) ALDH1A1MGLLLMNAMAPTNPSR1
SCHEMBL10297379 0.74 MGLL (0.37) ALDH1A1MGLL
SCHEMBL16786513 0.74 ALDH1A1 (0.38) ALDH1A1MGLLLMNAMAPTNPSR1
SCHEMBL17206671 0.72 ALDH1A1 (0.34) ALDH1A1MGLLLMNAMAPTNPSR1
SCHEMBL9918955 0.72 TDP1 (0.33) MGLL
SCHEMBL21164172 0.72 MGLL (0.44) ALDH1A1MGLLLMNAMAPTNPSR1
SCHEMBL15599422 0.71 MGLL (0.40) ALDH1A1MGLLLMNAMAPTNPSR1
SCHEMBL15834901 0.71 TDP1 (0.33) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490460-B1 LUBRICATING COMPOSITIONS WITH GOOD THERMAL STABILITY AND DEMULSIBILITY PROPERTIES LUBRIZOL CORP (US) 2011-06-22 EP disclosed
EP-1252277-B1 LUBRICANTS WITH THE COMBINATION OF A MOLYBDENUM COMPOUND, A PHOSPHORUS COMPOUNDS AND DISPERSANTS LUBRIZOL CORP (US) 2010-05-05 EP disclosed
EP-1200540-A4 MINERAL GEAR OILS AND TRANSMISSION FLUIDS LUBRIZOL CORP (US) 2008-09-03 EP disclosed
EP-1313826-B1 EXTENDED DRAIN MANUAL TRANSMISSION LUBRICANTS AND CONCENTRATES LUBRIZOL CORP (US) 2007-10-17 EP disclosed
CN-100334188-C Lubricating compositions with good thermal stability and demulsibility properties LUBRIZOL CORP (US) 2007-08-29 CN disclosed
US-6962895-B2 Lubricating compositions THE LUBRIZOL CORPORATION (US) 2005-11-08 US disclosed
CN-1649987-A Lubricating compositions with good thermal stability and demulsibility properties LUBRIZOL CORP (US) 2005-08-03 CN disclosed
US-6890890-B2 Lubricants with the combination of a molybdenum compound, a phosphorus compounds and dispersants THE LUBRIZOL CORPORATION (US) 2005-05-10 US disclosed
US-6872693-B2 Mineral gear oils and transmission fluids THE LUBRIZOL CORPORATION (US) 2005-03-29 US disclosed
EP-1490460-A1 LUBRICATING COMPOSITIONS WITH GOOD THERMAL STABILITY AND DEMULSIBILITY PROPERTIES THE LUBRIZOL CORPORATION (US) 2004-12-29 EP disclosed
WO-1992018589-A1 LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1992-10-29 WO disclosed
US-5154843-A Improved anti-wear and extreem pressure properties; salts formed with bases including detergents, dispersant and amines THE LUBRIZOL CORPORATION (US) 1992-10-13 US disclosed
US-5059335-A LUBRICANTS CONTAINING SALTS OF HYDROXYALKANE PHOSPHONIC ACIDS THE LUBRIZOL CORPORATION (US) 1991-10-22 US disclosed
EP-0419595-A1 LUBRICANTS CONTAINING SALTS OF HYDROXYALKANE PHOSPHONIC ACIDS. LUBRIZOL CORP (US) 1991-04-03 EP disclosed
EP-0408735-A1 HYDROXYALKANE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF AND LUBRICANTS CONTAINING THE SAME. LUBRIZOL CORP (US) 1991-01-23 EP disclosed
WO-1990009425-A1 LUBRICANTS CONTAINING SALTS OF HYDROXYALKANE PHOSPHONIC ACIDS THE LUBRIZOL CORPORATION (US) 1990-08-23 WO disclosed
WO-1990009386-A1 HYDROXYALKANE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF AND LUBRICANTS CONTAINING THE SAME THE LUBRIZOL CORPORATION (US) 1990-08-23 WO disclosed
EP-0287569-A1 OIL-SOLUBLE REACTION PRODUCTS OF AN ACYLATED REACTION PRODUCT, A POLYAMINE, AND A MONO-FUNCTIONAL ACID. LUBRIZOL CORP (US) 1988-10-26 EP disclosed
WO-1987003897-A1 OIL-SOLUBLE REACTION PRODUCTS OF AN ACYLATED REACTION PRODUCT, A POLYAMINE, AND A MONO-FUNCTIONAL ACID THE LUBRIZOL CORPORATION (US) 1987-07-02 WO disclosed
US-4670173-A DISPERSANTS; VISCOSITY IMPROVERS; GEL-FREE THE LUBRIZOL CORPORATION (US) 1987-06-02 US disclosed